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Course profile

Biochemistry & Molecular Biology (BIOC2000)

Study period
Sem 1 2026
Location
St Lucia
Attendance mode
In Person

Course overview

Study period
Semester 1, 2026 (23/02/2026 - 20/06/2026)
Study level
Undergraduate
Location
St Lucia
Attendance mode
In Person
Units
2
Administrative campus
St Lucia
Coordinating unit
Chemistry & Molec Biosciences

This course will enable you to gain an understanding of the key concepts of biochemistry and molecular biology. At the end of the course you will have an understanding of how proteins can catalyse the chemical reactions that allow cells to function. To get to this point you will gain an understanding of: the nature of chemical reactions in biological systems; how genetic information is used to direct protein synthesis; how the structure of proteins is determined; how structure determines function; and how we understand the properties of enzymes. You will be able to reinforce and apply these concepts in laboratory practicals where you will purify and characterise a protein.

An understanding of cellular processes at the molecular level is central to contemporary biological and biomedical sciences. The principles and practise of biochemistry and molecular biology form the basis for that understanding. The focus of BIOC2000 is the molecular components of cells: protein structure and function, enzymes and catalysis, DNA structure and function, and the links between disease and cellular metabolism. In conjunction with BIOC2001, BIOL2202 and MICR2000, BIOC2000 is a commonly recommended course in various Fields of Study in The University of Queensland Bachelor of Science program. BIOC2000 is essential for Biochemistry and Molecular Biology Major students.

Course requirements

Prerequisites

You'll need to complete the following courses before enrolling in this one:

[BIOL1020 or BIOM1050 or BIOM1051 or CHEE1001 or BIOE1001] AND [CHEM1100 or CHEM1221 or CHEM1222]

Incompatible

You can't enrol in this course if you've already completed the following:

AGRC2001, BIOC2012, BIOC2014, BIOC2900 (advanced version)

Course contact

Course staff

Lecturer

Timetable

The timetable for this course is available on the UQ Public Timetable.

Additional timetable information

Check your online timetable regularly.

Aims and outcomes

The aim of this course is to familiarize students with biomolecules (the molecules of life). Students will become familiar with proteins, DNA, RNA, lipids, and carbohydrates and their structures and roles in cells. The focus of the course is at the biochemical, metabolic, and basic bioinformatics level. Completion of this course will assure a sound basis for biochemistry, molecular biology, biomedical science, physiology, cell biology, and pharmacology studies.

Learning outcomes

After successfully completing this course you should be able to:

LO1.

Describe the chemical and physical forces driving biomolecular folding and interactions, then apply this knowledge to analysis of structures and functions of biomolecules.

LO2.

Apply your understanding of transcription and translation to develop a molecular cloning strategy.

LO3.

Interpret and analyse enzymatic function and kinetics.

LO4.

Predict the impact of altering the components of a metabolic pathway.

LO5.

Demonstrate theoretical and practical mastery of a range of crucial protein and DNA-related laboratory skills by working in the laboratory and producing a written report about your laboratory work.

LO6.

Discuss, in an informed manner, the most revolutionary techniques in molecular biology and biochemistry such as restriction enzymes, PCR, GFP, and fusion proteins.

LO7.

Relate observed biological phenomena to key underlying concepts of biochemistry.

Assessment

Assessment summary

Category Assessment task Weight Due date
Paper/ Report/ Annotation, Quiz Understanding Laboratory Protocols
  • Hurdle
  • Identity Verified
  • In-person
17.5% for the in-class quiz; pass/fail for worksheet completion.

Worksheets to be completed in each laboratory session. 2/03/2026 - 11/05/2026

In-person, in-class quiz 18/05/2026 - 22/05/2026

Examination In-semester Exam
  • Hurdle
  • Identity Verified
  • In-person
20%

In-semester Saturday

28/03/2026 - 2/05/2026

Paper/ Report/ Annotation Laboratory Report 30%

27/05/2026 2:00 pm

Examination End-of-semester exam
  • Hurdle
  • Identity Verified
  • In-person
32.5%

End of Semester Exam Period

6/06/2026 - 20/06/2026

A hurdle is an assessment requirement that must be satisfied in order to receive a specific grade for the course. Check the assessment details for more information about hurdle requirements.

Assessment details

Understanding Laboratory Protocols

  • Hurdle
  • Identity Verified
  • In-person
Mode
Written
Category
Paper/ Report/ Annotation, Quiz
Weight
17.5% for the in-class quiz; pass/fail for worksheet completion.
Due date

Worksheets to be completed in each laboratory session. 2/03/2026 - 11/05/2026

In-person, in-class quiz 18/05/2026 - 22/05/2026

Task description

This assessment item consists of two parts:

  1. In-lab worksheets, each related to one of the eight (8) laboratory sessions (Pass/Fail). These will be released to you prior to the lab sessions and you will then complete these in the lab sessions. A pass mark will be awarded for a worksheet by showing your tutor a genuine attempt at the tasks BEFORE leaving the lab session. You will be required to gain a pass mark for ≥75% of the worksheets. These worksheets are formative and will aid you in learning the key concepts that will be tested in the in-class quiz. Additional self-test questions will be available on Blackboard.
  2. In-person, in-class quiz (17.5%). You will complete an in-class quiz that relates to an experimental scenario that will be released to you early in semester. You will be asked questions about the approach used in the scenario, the appropriate analysis of data generated in the scenario, and the conclusions that can be reached. The quizzes will be held in Week 12 and will be timetabled to match your timetabled laboratory session.

Use of Artificial Intelligence (AI) and Machine Translation (MT)

This assessment task is to be completed in-person. The use of generative Artificial Intelligence (AI) or Machine Translation (MT) tools will not be permitted. Any attempted use of AI or MT may constitute student misconduct under the Student Code of Conduct.

Practical absences (complete details in Blackboard)

You must complete 100% of the laboratory component of this course (Assessment Hurdles - under Additional Course Grading Information).

If you cannot complete your timetabled practical session because of circumstances beyond your control (e.g., illness), you must submit an online practical absence request through the Practical Absences link in Blackboard and attach supporting documentation that covers the date of the missed practical. There are limits to the number of applications you may submit (please see Blackboard for details).

Applications must be received within 24 hours of your practical session.

Hurdle requirements

See ADDITIONAL COURSE GRADING INFORMATION for the hurdle/s relating to this assessment item.

Submission guidelines

Worksheets should be attempted in the relevant lab sessions. The in-class quiz will be a paper-based, written quiz and will be completed in your scheduled session.

Deferral or extension

You may be able to defer this exam.

As the worksheets are formative in nature, no extensions or deferral is permitted for these.

You may be able to apply to defer the in-class quiz.

In-semester Exam

  • Hurdle
  • Identity Verified
  • In-person
Mode
Written
Category
Examination
Weight
20%
Due date

In-semester Saturday

28/03/2026 - 2/05/2026

Task description

This will be an on-campus, invigilated exam. The exam will be held on a Saturday to be decided by central examinations.

You will be allowed to take one double-sided A4 sheet of handwritten notes into the exam. Notes written on a tablet and then printed will NOT be accepted. This exam will test content from the lectures and contacts (workshop style activities) in Weeks 1-4 ONLY.

A single viewing session will be held AFTER any deferred examinations have taken place and have been marked, at a time when all of the relevant examiners are available.

UNIVERSITY-WIDE APPROVED CALCULATORS: You are likely to find a calculator useful when completing this exam. If you want to use a calculator in the exam it must comply with the University's Approved Calculator List, whereby the University maintains a list of approved non-programmable calculators for use in examinations. Students are permitted to use only such approved and labelled calculators. Students using the preferred model of calculator (Casio FX-82 series), may use it in examinations without pre-approval. Students must present all other calculators (assuming the model is on the list) to Student Central and have an approval label affixed to it. The labels are tamper-evident and cannot be removed without being destroyed. Exam invigilators will check for the existence of such labels. Information on this list may be found at https://my.uq.edu.au/services/manage-my-program/exams-and-assessment/sitting-exam/calculators-in-exams. Students must acquire either the preferred model of calculator or a model approved and labelled (at Student Central) before sitting any examination. Please note that having a calculator (other than the preferred model) that appears on the approved calculator list is not sufficient if you have not had your calculator labelled. Calculators need only be approved once.

Use of Artificial Intelligence (AI) and Machine Translation (MT)

This assessment task is to be completed in-person. The use of generative Artificial Intelligence (AI) or Machine Translation (MT) tools will not be permitted. Any attempted use of AI or MT may constitute student misconduct under the Student Code of Conduct.

Hurdle requirements

See ADDITIONAL COURSE GRADING INFORMATION for the hurdle/s relating to this assessment item.

Exam details

Planning time 10 minutes
Duration 60 minutes
Calculator options

(In person) Casio FX82 series only or UQ approved and labelled calculator

Open/closed book Closed book examination - specified written materials permitted
Materials

One A4 sheet of handwritten notes, double sided, is permitted

Exam platform Paper based
Invigilation

Invigilated in person

Submission guidelines

Deferral or extension

You may be able to defer this exam.

Laboratory Report

Mode
Written
Category
Paper/ Report/ Annotation
Weight
30%
Due date

27/05/2026 2:00 pm

Task description

In this assessment you will submit report that includes analysis of data you have collected in the laboratory practicals and figures suitable for publication in a scientific journal that show these data.

A template document will be provided for the report.

Your report must include:

  • an introduction that describes the biological and experimental context of what you did in the lab. This section must be fully referenced.
  • the curated data (e.g., identification and removal (if appropriate) of outliers, determination of means and standard deviations of repeated measures etc.)
  • high quality figures that shows the standard curve(s) accompanied by a figure legend
  • calculation of any unknown values using the standard curve(s)
  • a discussion section that assesses the experimental outcomes with reference to the aims of the work. This section should also address and discuss the quality and reliability of the data, and the limitations of the experimental approaches used. This section must be fully referenced.

Use of Artificial Intelligence (AI) and Machine Translation (MT)

This task has been designed to be challenging, authentic and complex. Whilst students may use AI and/or MT technologies, successful completion of assessment in this course will require students to critically engage in specific contexts and tasks for which artificial intelligence will provide only limited support and guidance.

A failure to reference generative AI or MT use may constitute student misconduct under the Student Code of Conduct.

To pass this assessment, students will be required to demonstrate detailed comprehension of their written submission independent of AI and MT tools.

Submission guidelines

This assignment must be submitted via the appropriate Turnitin submission point found on the course Blackboard site. Penalties may apply if your submission is late. It is your responsibility to ensure that your submission is complete.

Deferral or extension

You may be able to apply for an extension.

The maximum extension allowed is 28 days. Extensions are given in multiples of 24 hours.

Extension applications must be received no later than 24 hours after the published assessment due date and time.

Read the information contained in the following links carefully before submitting an application for extension to assessment due date.

For guidance on applying for an extension, information is available here.

For the policy relating to extensions, information is available here (Part D).

Information on medical certificates

Please note the University's requirements for medical certificates here.

Late submission

A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.

You are required to submit assessable items on time. If you fail to meet the submission deadline for any assessment item, then 10% of the maximum possible mark for the assessment item (assessment ‘marked from’ value) will be deducted as a late penalty for every day (or part day) late after the due date. For example, if you submit your assignment 1 hour late, you will be penalised 10%; if your assignment is 24.5 hours late, you will be penalised 20% (because it is late by one 24-hour period plus part of another 24-hour period). 10% will be deducted per day for up to 7 calendar days, at which point your submission will receive a mark of zero (0) unless an extension has been approved.

In most instances one or more hurdles will apply to your assessment item so you will need to submit it to fulfil the requirements of the course regardless of how late it is and the mark you are likely to be awarded.

End-of-semester exam

  • Hurdle
  • Identity Verified
  • In-person
Mode
Written
Category
Examination
Weight
32.5%
Due date

End of Semester Exam Period

6/06/2026 - 20/06/2026

Task description

This will be an on-campus, invigilated exam. The exam will occur in the Semester 1 exam weeks at a date and time determined by UQ Examinations.

You will be allowed to take one double-sided A4 sheet of handwritten notes into the exam. Notes written on a tablet and then printed will NOT be accepted. This exam will test content from the lectures and contacts (workshop style activities) in Weeks 5-13.

UNIVERSITY-WIDE APPROVED CALCULATORS: You are likely to find a calculator useful when completing this exam. If you want to use a calculator in the exam it must comply with the University's Approved Calculator List, whereby the University maintains a list of approved non-programmable calculators for use in examinations. Students are permitted to use only such approved and labelled calculators. Students using the preferred model of calculator (Casio FX-82 series), may use it in examinations without pre-approval. Students must present all other calculators (assuming the model is on the list) to Student Central and have an approval label affixed to it. The labels are tamper-evident and cannot be removed without being destroyed. Exam invigilators will check for the existence of such labels. Information on this list may be found at https://my.uq.edu.au/services/manage-my-program/exams-and-assessment/sitting-exam/calculators-in-exams. Students must acquire either the preferred model of calculator or a model approved and labelled (at Student Central) before sitting any examination. Please note that having a calculator (other than the preferred model) that appears on the approved calculator list is not sufficient if you have not had your calculator labelled. Calculators need only be approved once.

Use of Artificial Intelligence (AI) and Machine Translation (MT)

This assessment task is to be completed in-person. The use of generative Artificial Intelligence (AI) or Machine Translation (MT) tools will not be permitted. Any attempted use of AI or MT may constitute student misconduct under the Student Code of Conduct.

Hurdle requirements

See ADDITIONAL COURSE GRADING INFORMATION for the hurdle/s relating to this assessment item.

Exam details

Planning time 10 minutes
Duration 90 minutes
Calculator options

(In person) Casio FX82 series only or UQ approved and labelled calculator

Open/closed book Closed book examination - specified written materials permitted
Materials

One A4 sheet of handwritten notes, double sided, is permitted

Exam platform Paper based
Invigilation

Invigilated in person

Submission guidelines

Deferral or extension

You may be able to defer this exam.

Course grading

Full criteria for each grade is available in the Assessment Procedure.

Grade Description
1 (Low Fail)

Absence of evidence of achievement of course learning outcomes.

Course grade description: Work of a very poor quality showing a very limited understanding of subject matter and a very low level of appreciation of issues covered in lecture and laboratory programs. The minimum percentage required for this grade is: 0%

2 (Fail)

Minimal evidence of achievement of course learning outcomes.

Course grade description: Work of poor quality showing a very limited understanding of subject matter and a low level of appreciation of issues covered in lecture and laboratory programs. The minimum percentage required for this grade is: 30%

3 (Marginal Fail)

Demonstrated evidence of developing achievement of course learning outcomes

Course grade description: Fail: Falls short of satisfying all basic requirements for a Pass. The minimum percentage required for this grade is: 45%

4 (Pass)

Demonstrated evidence of functional achievement of course learning outcomes.

Course grade description: Work of fair quality demonstrating a basic understanding of most aspects of subject matter and a modest appreciation of issues covered in lecture and laboratory programs, but with serious deficiencies in some areas, at least good laboratory skills and a sound ability to interpret experimental results. The minimum percentage required for this grade is: 50%

5 (Credit)

Demonstrated evidence of proficient achievement of course learning outcomes.

Course grade description: Work of a good quality demonstrating a good understanding of most subject matter and a competent level of appreciation of issues covered in lecture and laboratory programs, although possibly with some lapses and inadequacies, at least good laboratory skills and a sound ability to interpret experimental results. The minimum percentage required for this grade is: 65%

6 (Distinction)

Demonstrated evidence of advanced achievement of course learning outcomes.

Course grade description: Work of a very good quality demonstrating a strong understanding of a wide, but not complete, range of subject matter and a good level of appreciation of issues, although not necessarily of the finer points, covered in lecture and laboratory programs, very good laboratory skills and a very good ability to interpret experimental results. The minimum percentage required for this grade is: 75%

7 (High Distinction)

Demonstrated evidence of exceptional achievement of course learning outcomes.

Course grade description: Work of exceptional quality showing a deep understanding of a wide range of subject matter and a clear appreciation of issues covered in lecture and laboratory programs, very good laboratory skills and a very good ability to interpret experimental results. The minimum percentage required for this grade is: 85%

Additional course grading information

Assessment Hurdles

In order to pass this course, you must meet ALL of the following requirements (if you do not meet these requirements, the maximum grade you will receive will be a 3):

  1. You must obtain a minimum weighted mark of 40% or more across the two examination components; and
  2. You must complete 100% of the laboratory component of the course.

Supplementary assessment

Supplementary assessment is available for this course.

Should you fail a course with a grade of 3, you may be eligible for supplementary assessment. Refer to my.UQ for information on supplementary assessment and how to apply.

Supplementary assessment provides an additional opportunity to demonstrate you have achieved all the required learning outcomes for a course.

If you apply and are granted supplementary assessment, the type of supplementary assessment set will consider which learning outcome(s) have not been met.

Supplementary assessment can take any form (such as a written report, oral presentation, examination or other appropriate assessment) and may test specific learning outcomes tailored to the individual student, or all learning outcomes.

To receive a passing grade of 3S4, you must obtain a mark of 50% or more on the supplementary assessment.

Additional assessment information

Assessment Submission

It is the responsibility of the student to ensure the on time, correct and complete submission of all assessment items.

Students are responsible for retaining evidence of submission by the due date for all assessment items, in the required form (for example, screenshot, email, photo, and an unaltered copy of submitted work).

In the case of a Blackboard outage, contact the Course Coordinator as soon as possible to confirm the outage with ITS.

Assessment/Attendance

Notify your Course Coordinator as soon as you become aware of any issue that may affect your ability to meet the assessment/attendance requirements of the course. The my.UQ website and the Course Profile (CP) for your course provide information about your course requirements, the rules associated with your courses and services offered by the University.

A note for repeating students in this course

Only learning activities and/or assessment items completed during the study period of enrolment, including any approved extensions, may contribute to your grade in this course. The whole or partial use of assessment items previously submitted for the same course, for a course at any institution, or for published material, is not permitted without written permission of the Course Coordinator.

Important Note

Turnitin is to be used for assignments/laboratory reports to check for plagiarism. Penalties can be severe for plagiarism.

The University has adopted the following definition of plagiarism: Plagiarism is the act of misrepresenting as one's own original work the ideas, interpretations, words or creative works of another either intentionally or unintentionally. These include published and unpublished documents, designs, music, sounds, images, photographs, computer codes and ideas gained through working in a group. These ideas, interpretations, words or works may be found in print and/or electronic media.

Students should read the UQ Student Integrity and Misconduct Policy.

Practical absences (complete details in Blackboard)

You must complete 100% of the laboratory component of this course (Assessment Hurdles - under Additional Course Grading Information).

If you cannot complete your timetabled practical session because of circumstances beyond your control (e.g., illness), you must submit an online practical absence request through the Practical Absences link in Blackboard and attach supporting documentation that covers the date of the missed practical. There are limits to the number of applications you may submit (please see Blackboard for details).

Applications must be received within 24 hours of your practical session.

Learning resources

You'll need the following resources to successfully complete the course. We've indicated below if you need a personal copy of the reading materials or your own item.

Library resources

Library resources are available on the UQ Library website.

Other course materials

If we've listed something under further requirement, you'll need to provide your own.

Required

Item Description Further Requirement
Lab coat A lab coat is part of the essential personal protective equipment (PPE) required for working in the teaching lab. own item needed
Safety glasses/goggles Lab safety glasses/goggles are part of the essential personal protective equipment (PPE) required for working in the teaching lab. own item needed
Lab notebook A suitable notebook is needed to record your activities in the lab. A recommendation of which notebook is suitable will be provided on Blackboard. own item needed
SnapGene Viewer software You can download this software package for free from the SnapGene website. Instructions will be given on Blackboard.

Additional learning resources information

Blackboard

Additional learning material will be available on the Blackboard site for BIOC2000. You can access these at learn.uq.edu.au.

Please check the Announcements section of the Blackboard site for information updates.

Although we will be working heavily from Lehninger, other Biochemistry and Molecular Biology texts are always a good additional resource. Reading things from more than one perspective can really help fill gaps in your understanding. The UQ Library has many good biochemistry texts available, and you will likely be able to pick up second-hand copies of Lehninger and other texts from past students.

Software

As a student in BIOC2000 it is essential that you source the software package SnapGene Viewer and install it on your laptop – this is a software package that allows you to visualise and interrogate nucleic acid sequence data to enable you to complete tasks in Laboratory Session 2. You can download this from the SnapGene website.

Learning activities

The learning activities for this course are outlined below. Learn more about the learning outcomes that apply to this course.

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Learning period Activity type Topic
Week 1

(23 Feb - 01 Mar)

Lecture

Course Introduction & Bioenergetics

Lecturer: Justin Ridge

Multiple weeks

From Week 2 To Week 3
(02 Mar - 15 Mar)

Lecture

Proteins and how we engineer them

Lecturer: Justin Ridge

Multiple weeks

From Week 2 To Week 11
(02 Mar - 17 May)

Practical

LEAPS Laboratory Sessions

Multiple weeks

From Week 4 To Week 5
(16 Mar - 29 Mar)

Lecture

Protein Structure & Function

Lecturer: Ben Schulz

Multiple weeks

From Week 7 To Week 10
(13 Apr - 10 May)

Lecture

Enzymology

Lecturer: Elizabeth Gillam

Multiple weeks

From Week 11 To Week 13
(11 May - 31 May)

Lecture

Metabolism

Lecturer: Justin Ridge

Additional learning activity information

A detailed outline of lecture content is available on the course Blackboard site.

Policies and procedures

University policies and procedures apply to all aspects of student life. As a UQ student, you must comply with University-wide and program-specific requirements, including the:

Learn more about UQ policies on my.UQ and the Policy and Procedure Library.