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Course profile

Introduction to Molecular Biology Laboratory (BIOC6001)

Study period
Sem 2 2024
Location
St Lucia
Attendance mode
In Person

Course overview

Study period
Semester 2, 2024 (22/07/2024 - 18/11/2024)
Study level
Postgraduate Coursework
Location
St Lucia
Attendance mode
In Person
Units
2
Administrative campus
St Lucia
Coordinating unit
Chemistry & Molec Biosciences

This course will introduce you to key skills required to carry out modern molecular biological research. By the end of this course, you will have an understanding of how many commonly used molecular biological techniques work, as well as their advantages and limitations, together with the fundamentals of experimental design and the ethical considerations of research. To get to this point you will reinforce and apply material learnt in lectures and tutorials in regular laboratory practical sessions where the detection, quantification, characterisation, and purification of proteins and nucleic acids will be explored.

BIOC6001 Introduction to Molecular Biology Laboratory has been designed to meet the needs of people from a variety of professional backgrounds, but in particular those undertaking training in the biological sciences including molecular biology, biotechnology and bioinformatics. The main emphasis of this course is to provide a deeper understanding of the most commonly used techniques in molecular biology and will also provide hands-on experience of these laboratory techniques.ᅠCompletion of this course will provide the foundational knowledge required for BIOC7001.

Course requirements

Assumed background

It is assumed that students taking this course will have foundational biological and chemical knowledge either from their previous studies or through taking foundational courses as part of their study plan.

Incompatible

You can't enrol in this course if you've already completed the following:

BIOC6017

Restrictions

Internal offering only.

Course contact

Course staff

Lecturer

Timetable

The timetable for this course is available on the UQ Public Timetable.

Additional timetable information

More information about your timetabled activities can be found on the course Blackboard site.

Aims and outcomes

The aim of this course is to familiarise students with the commonly used techniques in the study of biological molecules. The focus of the course is understanding and applying laboratory techniques that are used every day in research laboratories around the world. Completion of this course will provide the foundational knowledge required for BIOC7001.

Learning outcomes

After successfully completing this course you should be able to:

LO1.

Understand and articulate the theoretical basis of common molecular biological techniques.

LO2.

Competently carry out common techniques in the laboratory.

LO3.

Describe and apply the principles of basic experimental design.

LO4.

Apply and describe practices that demonstrate scientific ethics.

LO5.

Collect, interpret and report molecular biological data.

LO6.

Present findings in common forms of scientific communication.

Assessment

Assessment summary

Category Assessment task Weight Due date
Practical/ Demonstration Assessment of laboratory performance
  • Hurdle
  • Identity Verified
  • In-person
25%

29/07/2024 - 8/10/2024

In your allocated practical session.

Examination In-Semester Exam
  • Hurdle
  • Identity Verified
  • In-person
20%

2/09/2024 6:00 pm

Creative Production/ Exhibition, Paper/ Report/ Annotation Communicating Molecular Biology
  • Hurdle
15%

9/10/2024 2:00 pm

Examination Final exam
  • Hurdle
  • Identity Verified
  • In-person
40%

End of Semester Exam Period

2/11/2024 - 16/11/2024

A hurdle is an assessment requirement that must be satisfied in order to receive a specific grade for the course. Check the assessment details for more information about hurdle requirements.

Assessment details

Assessment of laboratory performance

  • Hurdle
  • Identity Verified
  • In-person
Mode
Activity/ Performance, Oral
Category
Practical/ Demonstration
Weight
25%
Due date

29/07/2024 - 8/10/2024

In your allocated practical session.

Learning outcomes
L01, L02, L03, L05, L06

Task description

Assessment will be on the basis of how well each students attains the objectives of each practical session.

The students will be asked questions by the tutor (lab demonstrator) in every practical class. The students answers the questions orally, in class.

Attendance of practical classes is compulsory. See Additional Information for information on absence from practical sessions.

Use of Artificial Intelligence (AI)

This assessment task is to be completed in-person. The use of generative Artificial Intelligence (AI) tools will not be permitted. Any attempted use of Generative AI may constitute student misconduct under the Student Code of Conduct.

Hurdle requirements

See ADDITIONAL COURSE GRADING INFORMATION for the hurdle/s relating to this assessment item.

Submission guidelines

The students will be asked questions by the tutor (lab demonstrator) in every practical class. The students answers the questions orally, in class.

In addition to answering questions, the students are required to keep a record of their experimental data entered into the lab manual. The manual will be retained within the teaching laboratory until completion of the practical sessions.

Attendance of practical classes is compulsory. See Additional Information for information on absence from practical sessions.

Deferral or extension

You cannot defer or apply for an extension for this assessment.

See Additional Information for information on absence from practical sessions.

In-Semester Exam

  • Hurdle
  • Identity Verified
  • In-person
Mode
Written
Category
Examination
Weight
20%
Due date

2/09/2024 6:00 pm

Learning outcomes
L01, L03, L04, L05

Task description

This exam will assess material covered in the first 5 weeks of the course. 

Use of Artificial Intelligence (AI)

This assessment task is to be completed in-person. The use of generative Artificial Intelligence (AI) tools will not be permitted. Any attempted use of Generative AI may constitute student misconduct under the Student Code of Conduct.

Hurdle requirements

See ADDITIONAL COURSE GRADING INFORMATION for the hurdle/s relating to this assessment item.

Exam details

Planning time 10 minutes
Duration 60 minutes
Calculator options

(In person) Casio FX82 series or UQ approved , labelled calculator only

Open/closed book Closed Book examination - specified written materials permitted
Materials

1 A4 page, double sided, of handwritten notes

Exam platform Paper based
Invigilation

Invigilated in person

Submission guidelines

Deferral or extension

You may be able to defer this exam.

Communicating Molecular Biology

  • Hurdle
Mode
Product/ Artefact/ Multimedia, Written
Category
Creative Production/ Exhibition, Paper/ Report/ Annotation
Weight
15%
Due date

9/10/2024 2:00 pm

Learning outcomes
L01, L04, L06

Task description

BIOC6001 will introduce you to some of the most common techniques used in molecular biology. However, there are many other well-established procedures and protocols that can be used in the lab to achieve a specific goal – a simple search of the website of a molecular biology supplies company will hint at this diversity.

So, if you are looking to start using one of these protocols in your research how are you going to find out what it does and how it works? If you wanted to convince a funding body to give you the money in establishing the protocol in your lab, how might you explain it to them?

For this assessment item you must create two pieces of communication about a specific protocol that will be assigned to you:

  1. Promotional Flyer - A written piece, no longer than two pages, that explains to a junior researcher what the protocol achieves, how it works, and when it is appropriate to use it (like the advertising material used by molecular biology supplies companies)
  2. Video Explainer - A narrated video, of no more than 2.5 minutes, that explains the protocol to a member of the public, including what it can be used for or what it can generate (like a short piece you may see on a television news program).

The protocol assigned to you will be based on the concepts underlying the common techniques you will learn about in the lectures, practicals, and workshops. You will be expected to research the protocol you have been assigned to fully understand the molecular basis of the protocol, and what it is used for.

Use of Artificial Intelligence (AI)

This task has been designed to be challenging, authentic and complex. Whilst students may use AI technologies, successful completion of assessment in this course will require students to critically engage in specific contexts and tasks for which artificial intelligence will provide only limited support and guidance.

A failure to reference generative AI use may constitute student misconduct under the Student Code of Conduct.

To pass this assessment, students will be required to demonstrate detailed comprehension of their written submission independent of AI tools.

Hurdle requirements

See ADDITIONAL COURSE GRADING INFORMATION for the hurdle/s relating to this assessment item.

Submission guidelines

This assessment item requires the submission of two files.
1 - the Promotional Flyer must be submitted to the Turnitin portal available on the course Blackboard by the due date.
2 - the Video Explainer must be submitted to the Assessment portal available on the course Blackboard by the due date.

Deferral or extension

You may be able to apply for an extension.

Applications for Extensions

Information on applying for an extension can be found here: my.UQ Applying for an extension.

Extension applications must be received by the assessment due date and time.

If you are unable to provide approved documentation to support your application by the due date and time, you must still submit your application by the deadline but with an attached Word document that outlines why you cannot provide the approved documentation by the deadline. You will then need to acquire and upload the approved documentation to your request within 24 hours. Please note: When an extension request has been submitted and is pending, students are expected to continue to work on the assessment item, with the aim of submitting by the requested due date and time.

Prolonged Absence

If you have been ill or unable to attend class for more than 14 days, we advise you to carefully consider whether you are capable of successfully completing your courses this semester.

Extensions with Student Access Plans (SAP)

For extensions up to 7 days, your SAP is all that is required as documentation to support your application. However, extension requests longer than 7 days (for any one assessment item) will require the submission of additional supporting documentation e.g. a medical certificate.

Late submission

A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.

You are required to submit assessable items on time. If you fail to meet the submission deadline for any assessment item, then 10% of the maximum possible mark for the assessment item (assessment ‘marked from’ value) will be deducted as a late penalty for every day (or part day) late after the due date. For example, if you submit your assignment 1 hour late, you will be penalised 10%; if your assignment is 24.5 hours late, you will be penalised 20% (because it is late by one 24-hour period plus part of another 24-hour period). 10% will be deducted per day for up to 7 calendar days, at which point your submission will receive a mark of zero (0) unless an extension has been approved.

In most instances one or more hurdles will apply to your assessment item so you will need to submit it to fulfil the requirements of the course regardless of how late it is and the mark you are likely to be awarded.

Final exam

  • Hurdle
  • Identity Verified
  • In-person
Mode
Written
Category
Examination
Weight
40%
Due date

End of Semester Exam Period

2/11/2024 - 16/11/2024

Learning outcomes
L01, L03, L05

Task description

This exam will predominantly assess material covered in weeks 6-13 but material in the first 5 weeks of the course may be reassessed.

 

Hurdle requirements

See ADDITIONAL COURSE GRADING INFORMATION for the hurdle/s relating to this assessment item.

Exam details

Planning time 10 minutes
Duration 90 minutes
Calculator options

(In person) Casio FX82 series or UQ approved , labelled calculator only

Open/closed book Closed Book examination - specified written materials permitted
Materials

1 A4 page, double sided, of handwritten notes

Exam platform Paper based
Invigilation

Invigilated in person

Submission guidelines

Deferral or extension

You may be able to defer this exam.

Course grading

Full criteria for each grade is available in the Assessment Procedure.

Grade Description
1 (Low Fail)

Absence of evidence of achievement of course learning outcomes.

Course grade description: Student has made little attempt to address the requirements for this topic. Written submissions and performance are incomplete or unsatisfactory. The minimum percentage required for this grade is: 0%

2 (Fail)

Minimal evidence of achievement of course learning outcomes.

Course grade description: Student fails to demonstrate relevant knowledge or understanding of the underlying concepts associated with this topic. The student shows little evidence of the skills and understanding expected of a graduate. The minimum percentage required for this grade is: 30%

3 (Marginal Fail)

Demonstrated evidence of developing achievement of course learning outcomes

Course grade description: The student demonstrates a limited knowledge of the topics being assessed. The student shows little aptitude to continue in this area, but has benefited from the exercise and may be able to apply this knowledge for other purposes. The minimum percentage required for this grade is: 45%

4 (Pass)

Demonstrated evidence of functional achievement of course learning outcomes.

Course grade description: The student's answer to the topic is unambiguous and addresses the specific question(s) or issue(s) being examined. Performance in the assessment instrument(s) demonstrates basic knowledge and comprehension of the underlying concepts of the topic being examined. The minimum percentage required for this grade is: 50%

5 (Credit)

Demonstrated evidence of proficient achievement of course learning outcomes.

Course grade description: In addition to the criteria for a grade of 4, the student demonstrates in his or her assessment a superior understanding of some of the underlying concepts of the topic(s) being examined. The student has shown some competence in addressing the assessment criteria. The minimum percentage required for this grade is: 65%

6 (Distinction)

Demonstrated evidence of advanced achievement of course learning outcomes.

Course grade description: In addition to the criteria for a grade of 5, the student demonstrates a higher level of understanding of the factual and conceptual information available from the literature or other appropriate sources (e.g. the student's own experimental data). A good attempt has been made to dissect and integrate different aspects of that knowledge, resulting in well-balanced and appropriate conclusions and a commendable attempt to synthesize ideas. The minimum percentage required for this grade is: 75%

7 (High Distinction)

Demonstrated evidence of exceptional achievement of course learning outcomes.

Course grade description: Reserved for an outstanding performance which demonstrates a level of achievement superior to a grade of 6, and includes a substantial and original synthesis of ideas based on a critical analysis of the subject matter available to the student. The minimum percentage required for this grade is: 85%

Additional course grading information

Assessment Hurdles

In order to pass this course, you must meet ALL of the following requirements (if you do not meet these requirements, the maximum grade you will receive will be a 3):

1.ᅠYou must obtain an overall course mark of 50% or more; and

2. You must obtain a weighted average mark of 40% or more across the two examination components; and

3. You must obtain a minimum weighted average mark of 40% across all other non-examination course assessment items and learning tasks; and

4. You must attend 100% of the laboratory component of the course and complete and submit ALL laboratory assessments.

The maximum grade you will receive will be a 2 if you:

1. Obtain a weighted average mark of 30% or less across the two examination components; and/or

2. Obtain a weighted average mark of 30% or less on theᅠnon-examination course assessment items and learning tasks.

Supplementary assessment

Supplementary assessment is available for this course.

Should you fail a course with a grade of 3, you may be eligible for supplementary assessment. Refer to my.UQ for information on supplementary assessment and how to apply. 

Supplementary assessment provides an additional opportunity to demonstrate you have achieved all the required learning outcomes for a course.  

If you apply and are granted supplementary assessment, the type of supplementary assessment set will consider which learning outcome(s) have not been met.  

Supplementary assessment can take any form (such as a written report, oral presentation, examination or other appropriate assessment) and may test specific learning outcomes tailored to the individual student, or all learning outcomes. 

To receive a passing grade of 3S4, you must obtain a mark of 50% or more on the supplementary assessment. 

Additional assessment information

Practical absences

You must attend 100% of the laboratory component of this course (Assessment Hurdles - under Assessment > Additional Information).

If you cannot attend your timetabled practical session because of circumstances beyond your control (e.g., illness), you must submit an online practical absence request through the Practical Absences link in Blackboard and attach supporting documentation that covers the date of the missed practical. A list of acceptable reasons and required supporting documentation can be found at

https://my.uq.edu.au/information-and-services/manage-my-program/exams-and-assessment/applying-assessment-extension?p=1#1

Your request must be made prior to or on the day of the missed practical. It is your responsibility to submit an application and provide correct documentation by the due date and time. Requests without correct supporting documentation may not be approved. If the reason for your absence is not approved, you will be considered as absent from that practical session, and the laboratory attendance hurdle may apply.

Assessment Submission

It is the responsibility of the student to ensure the on time, correct and complete submission of all assessment items.

Please ensure you receive and save the submission confirmation for all submitted items, you may be asked to produce this as evidence of your submission.

Turnitin

By submitting work through Turnitin you are deemed to have accepted the following declaration “I certify that this assignment is my own work and has not been submitted, either previously or concurrently, in whole or in part, to this University or any other educational institution, for marking or assessment”.

All students must ensure they receive their Turnitin receipt on submission of any assessments. A valid Turnitin receipt will be the only evidence accepted if one or more of your submissions are missing. Without evidence, the assessment will receive the standard late penalty, or after seven days, will receive zero. In the case of a Blackboard outage, please contact the Course Coordinator as soon as possible to confirm the outage with ITS.

Assessment/Attendance

Please notify your Course Coordinator as soon as you become aware of any issue that may affect your ability to meet the assessment/attendance requirements of the course. The my.UQ website and the Electronic Course Profile (ECP) for your course also provide information about your course requirements, the rules associated with your courses and services offered by the University.

A note for repeating students in this course

Any student who enrols in a course must not be given exemption or partial credit from their previous attempt(s) for any individual piece of assessment. Instead, the student must successfully complete all of the learning activities and assessment items within the study period of enrolment (PPL Assessment - Procedures Section: Assessment integrity).

If the same assessment item is set from one year to the next, repeating students are allowed to submit the same work they submitted in previous attempts at the course. Where possible SCMB recommends that you use the feedback you received in your last attempt to improve parts of the item where you lost marks. Resubmission of an altered or unaltered assessment item by a repeating student (where the same assessment has been set) will not be considered as self-plagiarism.

Important Note

Turnitin is to be used for assignments/laboratory reports to check for plagiarism. Penalties can be severe for plagiarism.

The University has adopted the following definition of plagiarism: Plagiarism is the act of misrepresenting as one's own original work the ideas, interpretations, words or creative works of another either intentionally or unintentionally. These include published and unpublished documents, designs, music, sounds, images, photographs, computer codes and ideas gained through working in a group. These ideas, interpretations, words or works may be found in print and/or electronic media.

Students are encouraged to read the UQ Academic Integrity and Plagiarism policy.

Learning resources

You'll need the following resources to successfully complete the course. We've indicated below if you need a personal copy of the reading materials or your own item.

Library resources

Find the required and recommended resources for this course on the UQ Library website.

Additional learning resources information

Blackboard

Additional supplementary material may be posted on the Blackboard site at ᅠlearn.uq.edu.au

Please check the Announcements section of the Blackboard site regularly for information updates.

Learning activities

The learning activities for this course are outlined below. Learn more about the learning outcomes that apply to this course.

Filter activity type by

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Learning period Activity type Topic
Week 1
Lecture

Course Introduction & Scientific method

Learning outcomes: L03, L04, L05

Multiple weeks

From Week 2 To Week 3

Lecture

Module 1 - Working with numbers

Lecturer - Dr Evelyne Deplazes

Learning outcomes: L03, L05, L06

Multiple weeks

From Week 2 To Week 12

Practical

Laboratory Practicals

Learning outcomes: L01, L02, L03, L04, L05, L06

Multiple weeks

From Week 2 To Week 13

Workshop

Workshops

Learning outcomes: L01, L02, L03, L05, L06

Multiple weeks

From Week 3 To Week 8

Lecture

Module 2 - Working with nucleic acids

Lecturer - Dr Justin Ridge

Learning outcomes: L01, L03, L05, L06

Multiple weeks

From Week 9 To Week 13

Lecture

Module 3 - Working with proteins

Lecturer - Dr Simon Worrall

Learning outcomes: L01, L03, L05, L06

Policies and procedures

University policies and procedures apply to all aspects of student life. As a UQ student, you must comply with University-wide and program-specific requirements, including the:

Learn more about UQ policies on my.UQ and the Policy and Procedure Library.

You'll also need to be aware of the following policies and procedures while completing this course:

  • Laboratory Occupational Health and Safety