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Course profile

Functional Magnetic Resonance Imaging (MRES7008)

Study period
Sem 2 2025
Location
St Lucia
Attendance mode
In Person

Course overview

Study period
Semester 2, 2025 (28/07/2025 - 22/11/2025)
Study level
Postgraduate Coursework
Location
St Lucia
Attendance mode
In Person
Units
2
Administrative campus
St Lucia
Coordinating unit
Mathematics & Physics School

Interrogating sensory, motor & cognitive processes with functional magnetic resonance imaging (fMRI). Neural & vascular mechanisms contributing to the fMRI signal. Procedures involved in conducting fMRI investigations. Issues in experimental design & analysis. Relevance to clinical diagnosis. Current research status.

This course introduces functional magnetic resonance imaging (fMRI) methods used to study human brain function. Students will acquire a broad understanding of how MRI imaging is typically used in neuroscientific research and will conduct imaging experiments.

The topics to be covered include:

  • Introduction and history of brain mapping
  • Physiological basis of the BOLD signal.
  • MRI Physics for fMRI & Echo Planar Imaging (EPI) Principles
  • EPI Artefacts, Optimisation & Advanced Acquisition techniques
  • Experimental Design in fMRI
  • Running fMRI experiments
  • fMRI Data Preprocessing
  • Statistical analysis using the General Linear Model (GLM) for first-level (single-subject) and second-level (group) analysis.
  • Functional Connectivity Analysis
  • Clinical Applications of fMRI, including presurgical mapping, epilepsy and clinical research.
  • Practical hands-on analysis sessions

Course requirements

Assumed background

Undergraduate qualification in radiography, biomedical engineering or medical physics (or international equivalent)

Prerequisites

You'll need to complete the following courses before enrolling in this one:

Admission to Magnetic Resonance Technology postgraduate program suite + (MRES7001 or MRES7100) + MRES7004

Jointly taught details

This course is jointly-taught with:

  • Another instance of the same course

This course is offered internally and externally.

Course contact

Course staff

Lecturer

Invited lecturer

Timetable

The timetable for this course is available on the UQ Public Timetable.

Aims and outcomes

MRES7008 aims to introduce students to the functional MRI of the brain and provide a broad and detailed understanding of this branch of neuroscience. This course includes the opportunity to design functional brain imaging experiments, analyse task-based and resting-state fMRI data using the most popular research software (e.g., SPM, CONN), and draw conclusions based on the findings. Functional connectivity and clinical applications will also be discussed. This course will equip students with the ability to undertake fMRI research, identify common pitfalls, and critically interpret the findings of fMRI experiments.

Learning outcomes

After successfully completing this course you should be able to:

LO1.

Explain the physiological cascade from neural activity to the BOLD signal.

LO2.

Describe the MRI physics behind BOLD contrast, Echo Planar Imaging (EPI) and advanced fast imaging techniques used in fMRI studies.

LO3.

Design appropriate experimental paradigms for fMRI studies.

LO4.

Outline the practical and ethical steps for conducting an fMRI experiment.

LO5.

Apply a standard preprocessing pipeline to raw fMRI data.

LO6.

Implement the General Linear Model for first and second-level fMRI analysis.

LO7.

Analyse and interpret task-based and resting-state functional connectivity in the human brain.

LO8.

Critically evaluate fMRI research and its clinical applications. 

Assessment

Assessment summary

Category Assessment task Weight Due date
Quiz Online Quizes 20% equally weighted

Quiz 1 should be submitted prior to: 8/08/2025 5:00 pm

Quiz 2 should be submitted prior to: 15/08/2025 5:00 pm

Quiz 3 should be submitted prior to: 5/09/2025 5:00 pm

Quiz 4 should be submitted prior to: 19/09/2025 5:00 pm

Quiz 5 should be submitted prior to: 17/10/2025 5:00 pm

Essay/ Critique Essay - Written Assignment 20%

26/09/2025 5:00 pm

Paper/ Report/ Annotation, Presentation Report and Presentation
  • Identity Verified
20% specific weighting

Presentation slides are due: 17/10/2025 5:00 pm

Oral Presentation will be given in class 29/10/2025

Practical report is due: 31/10/2025 5:00 pm

Examination Final Examination
  • Hurdle
  • Identity Verified
  • In-person
40%

End of Semester Exam Period

8/11/2025 - 22/11/2025

A hurdle is an assessment requirement that must be satisfied in order to receive a specific grade for the course. Check the assessment details for more information about hurdle requirements.

Assessment details

Online Quizes

Mode
Written
Category
Quiz
Weight
20% equally weighted
Due date

Quiz 1 should be submitted prior to: 8/08/2025 5:00 pm

Quiz 2 should be submitted prior to: 15/08/2025 5:00 pm

Quiz 3 should be submitted prior to: 5/09/2025 5:00 pm

Quiz 4 should be submitted prior to: 19/09/2025 5:00 pm

Quiz 5 should be submitted prior to: 17/10/2025 5:00 pm

Task description

5x Online quizzes which are due throughout the Semester which assess knowledge on each of the delivered modules. Each quiz will be open from Monday until Friday in the week that it is due.  

Submission guidelines

Deferral or extension

You cannot defer or apply for an extension for this assessment.

An extension/deferral is not available for this quiz due to the answers being discussed in the next available tutorial. However, successful applications for an extension in extenuating circumstances may be offered an alternative assessment. If there are extenuating circumstances why you were unable to complete your quiz then please email smp.student@uq.edu.au. You will need to do this within 5 calendar days of your quiz and include evidence (e.g., medical certificate). 

Late submission

You will receive a mark of 0 if this assessment is submitted late.

The quizzes are open for 5 days (Monday to Friday) and cannot be accessed once closed. A 100% penalty will be applied if the quiz is not attempted within that period.  

Essay - Written Assignment

Mode
Written
Category
Essay/ Critique
Weight
20%
Due date

26/09/2025 5:00 pm

Task description

2000-word assignment (1000 words per scenario) on two scenario-based questions:

  • Scenario 1: Clinical Application - Design presurgical fMRI mapping protocol for a patient with temporal lobe epilepsy
  • Scenario 2: Research Application - Design an fMRI study investigating cognitive deficits in Mild Cognitive Impairment and Alzheimer’s Disease patients.


Submission guidelines

Your essay should be submited via Turnitin. Students are permitted to submit a draft prior to final submission.

Deferral or extension

You may be able to apply for an extension.

The maximum extension allowed is 28 days. Extensions are given in multiples of 24 hours.

See ADDITIONAL ASSESSMENT INFORMATION for the extension and deferred examination information relating to this assessment item.

Late submission

A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.

You are required to submit assessable items on time. If you fail to meet the submission deadline for any assessment item then the listed penalty will be deducted per day for up to 7 calendar days, at which point any submission will not receive any marks unless an extension has been approved. Each 24-hour block is recorded from the time the submission is due.

Report and Presentation

  • Identity Verified
Mode
Oral, Written
Category
Paper/ Report/ Annotation, Presentation
Weight
20% specific weighting
Due date

Presentation slides are due: 17/10/2025 5:00 pm

Oral Presentation will be given in class 29/10/2025

Practical report is due: 31/10/2025 5:00 pm

Task description

Part A: Written Practical Report (10%)

  • Task: You will use SPM (Statistical Parametric Mapping) software to analyse a publicly available fMRI dataset directed by the lecturer. You will choose one of the experimental tasks from this dataset (e.g., motor or language mapping) to perform a first-level (single-subject) and second-level (group) analysis.
  • Report Structure: Your report should be structured like a short scientific paper (Introduction, Methods, Results, Discussion, References, Appendix) and must be no more than 6 pages, including references. It should detail your analysis pipeline, justify your methodological choices, and present the results clearly, accompanied by figures and tables.
  • Due Date: 5pm on Friday, Week 13 (31/10/2025)
  • Submission: Submit via Turnitin


⠀Part B: PowerPoint Summary (5%)

  • Task: Create a concise PowerPoint presentation (maximum 8 slides, including title and references) that synthesises your written report. It should clearly outline the research question, methods, key results (including one primary figure), and conclusion.
  • Due Date: 5pm on Friday, Week 11 (17/10/2025)
  • Submission: Submit as a .pptx file via Blackboard.


⠀Part C: Oral Presentation (5%)

  • Task: You will give a 5-minute oral presentation to the class, based on your submitted PowerPoint slides. This will be followed by a brief 2-3 minute Q&A session. You should aim to clearly and concisely communicate your project's aims, methods, and findings.
  • Date: During the scheduled tutorial in Week 13 (Monday, 27 Oct 2025).


Submission guidelines

Presentation slides should be submitted via blackboard. The oral presentation will be given in class week 13. The practical report should be submitted via turnitin. Draft versions of the presentation and practical report can be submtted prior to the final submission.

Deferral or extension

You may be able to apply for an extension.

The maximum extension allowed is 28 days. Extensions are given in multiples of 24 hours.

Late submission

A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.

You are required to submit assessable items on time. If you fail to meet the submission deadline for any assessment item then the listed penalty will be deducted per day for up to 7 calendar days, at which point any submission will not receive any marks unless an extension has been approved. Each 24-hour block is recorded from the time the submission is due.

Final Examination

  • Hurdle
  • Identity Verified
  • In-person
Mode
Written
Category
Examination
Weight
40%
Due date

End of Semester Exam Period

8/11/2025 - 22/11/2025

Task description

The final exam will be an in-person, paper-based exam. Students enrolled externally, please refer to the course profile for External students for in-person examination arrangements.  

Hurdle requirements

See COURSE GRADING INFORMATION for the hurdle relating to this assessment item.

Exam details

Planning time 10 minutes
Duration 120 minutes
Calculator options

(In person) Casio FX82 series only or UQ approved and labelled calculator

Open/closed book Closed book examination - no written materials permitted
Exam platform Paper based
Invigilation

Invigilated in person

Submission guidelines

Deferral or extension

You may be able to defer this exam.

See ADDITIONAL ASSESSMENT INFORMATION for the extension and deferred examination information relating to this assessment item.

Course grading

Full criteria for each grade is available in the Assessment Procedure.

Grade Cut off Percent Description
1 (Low Fail) 0 - 19.5

Absence of evidence of achievement of course learning outcomes.

Course grade description: Fails to demonstrate most or all of the basic requirements of the course

2 (Fail) 20 - 44.5

Minimal evidence of achievement of course learning outcomes.

Course grade description: Demonstrates clear deficiencies in understanding and applying fundamental concepts; communicates information or ideas in ways that are frequently incomplete or confusing and give little attention to the conventions of the discipline

3 (Marginal Fail) 45 - 49.5

Demonstrated evidence of developing achievement of course learning outcomes

Course grade description: Demonstrates superficial or partial or faulty understanding of the fundamental concepts of the field of study and limited ability to apply these concepts; presents undeveloped or inappropriate or unsupported arguments; communicates information or ideas with lack of clarity and inconsistent adherence to the conventions of the discipline

4 (Pass) 50 - 64.5

Demonstrated evidence of functional achievement of course learning outcomes.

Course grade description: Demonstrates adequate understanding and application of the fundamental concepts of the field of study; develops routine arguments or decisions and provides acceptable justification; communicates information and ideas adequately in terms of the conventions of the discipline: Demonstrates adequate understanding of the range of fMRI experiments and experimental paradigms. Shows adequate understanding of the application of fMRI in the clinical setting. Shows adequate understanding of the factors influencing the design of functional MRI experiments and the steps involved in analysing data acquired from functional MRI experiments and has some knowledge of applying the techniques to solve both theoretical and practical problems related to fMRI experiments.

5 (Credit) 65 - 74.5

Demonstrated evidence of proficient achievement of course learning outcomes.

Course grade description: Demonstrates substantial understanding of fundamental concepts of the field of study and ability to apply these concepts in a variety of contexts; develops or adapts convincing arguments and provides coherent justification; communicates information and ideas clearly and fluently in terms of the conventions of the discipline:

6 (Distinction) 75 - 84.5

Demonstrated evidence of advanced achievement of course learning outcomes.

Course grade description: As for 5, with frequent evidence of originality in defining and analysing issues or problems and in creating solutions; uses a level, style and means of communication appropriate to the discipline and the audience

7 (High Distinction) 85 - 100

Demonstrated evidence of exceptional achievement of course learning outcomes.

Course grade description: As for 6, with consistent evidence of substantial originality and insight in identifying, generating and communicating competing arguments, perspectives or problem solving approaches; critically evaluates problems, their solutions and implications

Additional course grading information

A maximum of a grade of 3 will be awarded if less than 45% is achieved in the final examination.

Supplementary assessment

Supplementary assessment is available for this course.

Should you fail a course with a grade of 3, you may be eligible for supplementary assessment. Refer to my.UQ for information on supplementary assessment and how to apply. 

Supplementary assessment provides an additional opportunity to demonstrate you have achieved all the required learning outcomes for a course.  

If you apply and are granted supplementary assessment, the type of supplementary assessment set will consider which learning outcome(s) have not been met.  

Supplementary assessment in this course will be a 2-hour examination similar in style to the end-of-semester examination. To receive a passing grade of 3S4, you must obtain a mark of 50% or more on the supplementary assessment. 

Additional assessment information

Submission of Assignments

Submission of assignments by EMAIL will NOT BE ACCEPTED.

All written assignments eg. essays, reports, proposals, literature reviews etc must be submitted through Turnitin.

Turnitin submission

  1. Access the Assessment folder on the course Blackboard site
  2. Upload an electronic version through the assessment Turnitin site
  3. You will be sent a receipt, retain the receipt as proof of submission.
  4. If you don't receive a receipt, then your assignment has not been submitted - please re-submit.

Failure to submit on time will result in a late penalty being applied (see the assessment task for details). You need to ensure that you submitted by the due date, late submission will result in the late penalty being imposed.

PLAGIARISM: You should be aware that the University employs purpose-built software to detect plagiarism. It is very important that you understand clearly the practical meaning of plagiarism.

Students are encouraged to read the UQ Academic Integrity and Plagiarism policy (http://ppl.app.uq.edu.au/content/3.60.04-student-integrity-and-misconduct) which makes a comprehensive statement about the University's approach to plagiarism, including the approved use of plagiarism detection software, the consequences of plagiarism and the principles associated with preventing plagiarism.

DEFINITION OF PLAGIARISM: Plagiarism is the act of misrepresenting as one's own original work the ideas, interpretations, words or creative works of another. These include published and unpublished documents, designs, music, sounds, images, photographs, computer codes and ideas gained through working in a group. These ideas, interpretations, words or works may be found in print and/or electronic media.

EXAMPLES OF PLAGIARISM:

1. Direct copying of paragraphs, sentences, a single sentence or significant parts of a sentence;

2. Direct copying of paragraphs, sentences, a single sentence or significant parts of a sentence with an end reference but without quotation marks around the copied text;

3. Copying ideas, concepts, research results, computer codes, statistical tables, designs, images, sounds or text or any combination of these;

4. Paraphrasing, summarising or simply rearranging another person's words, ideas, etc without changing the basic structure and/or meaning of the text;

5. Offering an idea or interpretation that is not one's own without identifying whose idea or interpretation it is;

6. A 'cut and paste' of statements from multiple sources;

7. Presenting as independent, work done in collaboration with others;

8. Copying or adapting another student's original work into a submitted assessment item.

Artificial Intelligence

To pass this course, students will be required to demonstrate a detailed understanding of course material together with a range of associated skills independent of Artificial Intelligence (AI) and Machine Translation (MT) tools.

For assessment tasks that are completed in-person (including examinations) termed “secure assessment”, the use of generative Artificial Intelligence (AI) or Machine Translation (MT) tools will not be permitted unless otherwise advised. Any attempted use of AI or MT may constitute student misconduct under the Student Code of Conduct.

 Other non-secure assessment tasks (such as assignments) are designed to help you develop your understanding and skills, and to prepare you for secure assessment. You are thus generally encouraged to complete such assessment without the use of AI/MT, unless explicitly advised to the contrary in the assessment item. In any event, if you choose to use such tools, then you must clearly reference any such use within your submitted work. A failure to reference AI or MT use may constitute student misconduct under the Student Code of Conduct.

Applications for Extensions to Assessment Due Dates

Extension requests are submitted online via my.UQ – applying for an extension. Extension requests received in any other way will not be approved. Additional details associated with extension requests, including acceptable and unacceptable reasons, may be found at my.UQ.

Please note:

  • Requests for an extension to an assessment due date must be submitted through your my.UQ portal and you must provide documentation of your circumstances, as soon as it becomes evident that an extension is needed. Your application must be submitted on or before the assessment item's due date and time.
  • Applications for extension can take time to be processed so you should continue to work on your assessment item while awaiting a decision. We recommend that you submit any completed work by the due date, and this will be marked if your application is not approved. Should your application be approved, then you will be able to resubmit by the agreed revised due date.
  • If an extension is approved, you will be notified via your my.UQ portal and the new date and time for submission provided. It is important that you check the revised date as it may differ from the date that you requested.
  • If the basis of the application is a medical condition, applications should be accompanied by a medical certificate dated prior to the assignment due date. If you are unable to provide documentation to support your application by the due date and time you must still submit your application on time and attach a written statement (Word document) outlining why you cannot provide the documentation. You must then upload the documentation to the portal within 24 hours.
  • If an extension is being sought on the basis of exceptional circumstances, it must be accompanied by supporting documentation (eg. Statutory declaration).
  • For extensions based on a SAP you may be granted a maximum of 7 days (if no earlier maximum date applies). See the Extension or Deferral availability section of each assessment for details. Your SAP is all that is required as documentation to support your application. However, additional extension requests for the assessment item will require the submission of additional supporting documentation e.g., a medical certificate. All extension requests must be received by the assessment due date and time.
  • Students may be asked to submit evidence of work completed to date. Lack of adequate progress on your assessment item may result in an extension being denied.
  • If you have been ill or unable to attend class for more than 14 days, you are advised to carefully consider whether you are capable of successfully completing your courses this semester. You might be eligible to withdraw without academic penalty - seek advice from the Faculty that administers your program.
  • There are no provisions for exemption from an assessment item within UQ rules. If you are unable to submit an assessment piece then, under special circumstances, you may be granted an exemption, but may be required to submit alternative assessment to ensure all learning outcomes are met.

Applications to defer an exam

In certain circumstances you can apply to take a deferred examination for in-semester and end-of-semester exams. You'll need to demonstrate through supporting documentation how unavoidable circumstances prevented you from sitting your exam. If you can’t, you can apply for a one-off discretionary deferred exam.

Deferred Exam requests are submitted online via mySi-net. Requests received in any other way will not be approved. Additional details associated with deferred examinations, including acceptable and unacceptable reasons may be found at my.UQ.

Please note:

  • Applications can be submitted no later than 5 calendar days after the date of the original exam.
  • There are no provisions to defer a deferred exam. You need to be available to sit your deferred examination.
  • Your deferred examination request(s) must have a status of "submitted" in mySI-net to be assessed.
  • All applications for deferred in-semester examinations are assessed by the relevant school. Applications for deferred end-of-semester examinations are assessed by the Academic Services Division.
  • You’ll receive an email to your student email account when the status of your application is updated.
  • If you have a medical condition, mental health condition or disability and require alternative arrangements for your deferred exam you’ll need to complete the online alternative exam arrangements through my.UQ. This is in addition to your deferred examinations request. You need to submit this request on the same day as your request for a deferred exam or supplementary assessment. Contact Student Services if you need assistance completing your alternative exam arrangements request.

Learning resources

You'll need the following resources to successfully complete the course. We've indicated below if you need a personal copy of the reading materials or your own item.

Library resources

Library resources are available on the UQ Library website.

Learning activities

The learning activities for this course are outlined below. Learn more about the learning outcomes that apply to this course.

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Learning period Activity type Topic
Week 1

(28 Jul - 03 Aug)

Lecture

M1 - Introduction to fMRI & the BOLD Signal

Learning outcomes: L01

Week 2

(04 Aug - 10 Aug)

Lecture

M2 - MRI Physics for fMRI & Echo Planar Imaging (EPI) Principles

Learning outcomes: L01, L02

Week 3

(11 Aug - 17 Aug)

Lecture

EPI Artefacts, Optimization & Intro to Advanced Acquisition

Learning outcomes: L01, L02

Week 4

(18 Aug - 24 Aug)

Lecture

M4 - Experimental Design in fMRI

Learning outcomes: L01, L02, L03

Week 5

(25 Aug - 31 Aug)

Lecture

M5 - Running the experiment

Learning outcomes: L01, L02, L03, L04

Week 6

(01 Sep - 07 Sep)

Lecture

M6 - fMRI Data Preprocessing

Learning outcomes: L01, L02, L03, L04, L05

Week 7

(08 Sep - 14 Sep)

Lecture

Statistical Analysis I: GLM & First-Level Analysis

Week 8

(15 Sep - 21 Sep)

Lecture

Statistical Analysis II: Group Analysis & Multiple Comparisons

Week 9

(22 Sep - 28 Sep)

Applied Class

M9 - SPECIAL WEEK 1: Practical Task-based fMRI Analysis

Week 10

(06 Oct - 12 Oct)

Lecture

Functional Connectivity: Theory & Resting-State Networks

Week 11

(13 Oct - 19 Oct)

Lecture

Clinical Applications & Limitations of fMRI

Week 12

(20 Oct - 26 Oct)

Applied Class

SPECIAL WEEK 2: Practical Resting-State fMRI Connectivity

Week 13

(27 Oct - 02 Nov)

Applied Class

Presentation and Review

Policies and procedures

University policies and procedures apply to all aspects of student life. As a UQ student, you must comply with University-wide and program-specific requirements, including the:

Learn more about UQ policies on my.UQ and the Policy and Procedure Library.