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Course profile

MRI Pulse Sequence Construction & Image Contrast (MRES7400)

Study period
Sem 2 2025
Location
External
Attendance mode
Online

Course overview

Study period
Semester 2, 2025 (28/07/2025 - 22/11/2025)
Study level
Postgraduate Coursework
Location
External
Attendance mode
Online
Units
2
Administrative campus
St Lucia
Coordinating unit
Mathematics & Physics School

This course aims to equip students with a comprehensive understanding of Magnetic Resonance Imaging (MRI) sequences commonly used in clinical and research settings. Students will gain an in-depth understanding of the building blocks of MRI sequences, including radiofrequency (RF) pulses, magnetic field gradients, spatial encoding methods, and signal sampling. They will learn their characteristics and manipulation methods and how to combine them to form different sequences that produce images with various contrast weightings, such as proton density, T1-, T2, T2* and other contrasts.

Starting from the basic gradient-echo and spin-echo sequences, students will explore the composition and parameters of various sequences and how to vary them to achieve different contrasts. More advanced and emerging sequences will also be explored, enabling students to confidently manipulate scanner parameters and generate desired MRI contrast.

MR images are prone to artefacts from various sources, and identifying them is essential for MRI researchers and technicians. This course will introduce the different types of static and dynamic artefacts that commonly occur on MR images, explain their causes and the methods to eliminate or reduce them.

The skills and knowledge attained in this course will prepare students of the program for later courses in advanced applications of MRI and practical operation of MRI scanners within the clinical environment.

This foundational course is mandatory for the postgraduate Master of Magnetic Resonance Technology program. It provides essential background knowledge necessary for understanding subsequent courses in the program. It introduces the principles of practical MRI pulse sequence design and construction, applying them to analyse and understand the origin of the MRI signal and its contrast weighting in sequences that are critical for both clinical diagnostic imaging and research imaging.

Course requirements

Assumed background

This course assumes successful completion of MRES7100, Magnetic Resonance Imaging: Fundamentals

Recommended prerequisites

We recommend completing the following courses before enrolling in this one:

MRES7100

Incompatible

You can't enrol in this course if you've already completed the following:

MRES7004

Jointly taught details

This course is jointly-taught with:

  • Another instance of the same course

MRES7400 External and MRES7400 in-person are jointly taught.

Course contact

Course staff

Lecturer

Timetable

The timetable for this course is available on the UQ Public Timetable.

Additional timetable information

An additional tutorial session will be held after the lecture in some weeks for practical demonstrations and quiz question reviews. More information is available on the "Learning Activities" section.

Aims and outcomes

Upon finishing this course, students will gain a comprehensive understanding of the implementation and parameters of various clinically important and commonly used sequences. They will also gain an in-depth understanding of how the choice of sequence parameters affects the contrast of images. Students will be capable of identifying common artefacts on MR images and reducing them by changing the parameters.

Learning outcomes

After successfully completing this course you should be able to:

LO1.

Create MRI sequences by applying knowledge of magnetic field gradients and RF pulses.

LO2.

Predict the effect of adjusting sequence parameters on image contrast.

LO3.

Explain the performance of advanced sequences in producing the desired contrast.

LO4.

Understand the practical implementation and limitations of imaging sequences.

LO5.

Recognise and explain image artefacts and suggest approaches for their correction.

Assessment

Assessment summary

Category Assessment task Weight Due date
Quiz Online Quizzes Based on Modules
  • Online
30%

Quiz 1 - Entry test 8/08/2025 2:00 pm

Quiz 2 covering Module 2-4 22/08/2025 2:00 pm

Quiz 3 covering Module 5 and 6 5/09/2025 2:00 pm

Quiz 4 covering Module 7 and 8 19/09/2025 2:00 pm

Quiz 5 covering Module 9 and10 17/10/2025 2:00 pm

Each quiz is designed to cover the material of two modules, except Quiz 1, which tests fundamental MRI concepts. Quiz 1 will be available at the start of the course, and the other quizzes will be released before the lecture on the first module and due by 2:00 PM on the Friday following the lecture for the second module.

Paper/ Report/ Annotation Assignment Based on Practical Demonstration
  • Online
20%

10/10/2025 2:00 pm

A similarity check will be conducted on the submissions, and the similarity report will be released after the due date.

Examination Final Examination
  • Hurdle
  • Identity Verified
  • In-person
50%

End of Semester Exam Period

8/11/2025 - 22/11/2025

A hurdle is an assessment requirement that must be satisfied in order to receive a specific grade for the course. Check the assessment details for more information about hurdle requirements.

Assessment details

Online Quizzes Based on Modules

  • Online
Mode
Written
Category
Quiz
Weight
30%
Due date

Quiz 1 - Entry test 8/08/2025 2:00 pm

Quiz 2 covering Module 2-4 22/08/2025 2:00 pm

Quiz 3 covering Module 5 and 6 5/09/2025 2:00 pm

Quiz 4 covering Module 7 and 8 19/09/2025 2:00 pm

Quiz 5 covering Module 9 and10 17/10/2025 2:00 pm

Each quiz is designed to cover the material of two modules, except Quiz 1, which tests fundamental MRI concepts. Quiz 1 will be available at the start of the course, and the other quizzes will be released before the lecture on the first module and due by 2:00 PM on the Friday following the lecture for the second module.

Task description

Students are required to complete five online quizzes.

Submission guidelines

Students will submit their answers online. Only one attempt is allowed for each quiz.

Deferral or extension

You cannot defer or apply for an extension for this assessment.

An extension is not available for this quiz due to the answers being discussed in the next available tutorial. However, successful applications for an extension in extenuating circumstances may be offered an alternative assessment. If there are extenuating circumstances why you were unable to complete your quiz, then please email smp.student@uq.edu.au. You will need to do this within 5 calendar days of your quiz and include evidence (e.g., medical certificate).

Late submission

A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.

Students are required to submit the answers online before the due date. Otherwise, the penalty will be applied. Submissions received after the quiz tutorial session will be awarded zero marks. The tutorial is usually scheduled on the following Monday after the due date, after the lecture.

Assignment Based on Practical Demonstration

  • Online
Mode
Written
Category
Paper/ Report/ Annotation
Weight
20%
Due date

10/10/2025 2:00 pm

A similarity check will be conducted on the submissions, and the similarity report will be released after the due date.

Task description

Students will review practical demonstrations and related modules, answering questions related to the demonstration.

Submission guidelines

Students are required to submit their answers using the TurnItIn link available on Blackboard.

Deferral or extension

You may be able to apply for an extension.

Refer to the "ADDITIONAL ASSESSMENT INFORMATION" section for details on extension applications.

Late submission

A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.

You are required to submit assessable items on time. If you fail to meet the submission deadline for any assessment item then the listed penalty will be deducted per day for up to 7 calendar days, at which point any submission will not receive any marks unless an extension has been approved. Each 24-hour block is recorded from the time the submission is due.

Final Examination

  • Hurdle
  • Identity Verified
  • In-person
Mode
Written
Category
Examination
Weight
50%
Due date

End of Semester Exam Period

8/11/2025 - 22/11/2025

Task description

The final exam will be an in-person, paper-based exam. UQ Examinations will contact students directly to confirm arrangements; the student will either sit the exam at the St Lucia campus (lives within 200km radius of the campus) or will be directed to nominate an exam centre by a certain date. 

Please ensure you update your semester address in Si-net at the start of the semester.

One reminder will be sent and students who fail to nominate an exam centre and will be automatically assigned to the St Lucia campus. Late nominations will not be accepted.

A list of examination centres is listed here, but note that Exam centre availability is subject to change at short notice. 

Students enrolled internally, please refer to the course profile for Internal students for in-person examination arrangements.   

Hurdle requirements

See the "ADDITIONAL COURSE GRADING INFORMATION" section below.

Exam details

Planning time 10 minutes
Duration 120 minutes
Calculator options

(In person) Casio FX82 series only or UQ approved and labelled calculator

Open/closed book Open book examination - any written or printed material is permitted; material may be annotated
Materials

Any written or printed material is permitted; material may also be annotated.

Exam platform Paper based
Invigilation

Invigilated in person

Submission guidelines

Deferral or extension

You may be able to defer this exam.

Refer to the "ADDITIONAL ASSESSMENT INFORMATION" section for details on extension and deferred examination options.

Course grading

Full criteria for each grade is available in the Assessment Procedure.

Grade Description
1 (Low Fail)

Absence of evidence of achievement of course learning outcomes.

Course grade description: Demonstrates very limited understanding of the theory and practise of Magnetic Resonance Imaging, the source of MR contrast, the design of pulse sequences and of the basic concepts in the course material. This includes attempts at answering some questions but demonstrating very limited understanding of the key concepts. The minimum percentage required is: 0%

2 (Fail)

Minimal evidence of achievement of course learning outcomes.

Course grade description: Demonstrates limited understanding of the theory and practise of Magnetic Resonance Imaging, the source of MR contrast, the design of pulse sequences and demonstrates limited knowledge of the techniques used to solve problems. This includes attempts at expressing their deductions and explanations and attempts to answer a few questions accurately. The minimum percentage required is: 20%

3 (Marginal Fail)

Demonstrated evidence of developing achievement of course learning outcomes

Course grade description: Demonstrates some understanding of the theory and practise of Magnetic Resonance Imaging, the source of MR contrast, the design of pulse sequences and demonstrates knowledge of the techniques used to solve problems but an inability to apply these successfully. The minimum percentage required is: 45%

4 (Pass)

Demonstrated evidence of functional achievement of course learning outcomes.

Course grade description: Demonstrates an understanding of the theory and practise of Magnetic Resonance Imaging, the source of MR contrast, the design of pulse sequences and demonstrates knowledge of the techniques used to solve problems and can apply these successfully to some extent. The minimum percentage required is: 50%

5 (Credit)

Demonstrated evidence of proficient achievement of course learning outcomes.

Course grade description: Demonstrates a good understanding of the theory and practise of Magnetic Resonance Imaging, the source of MR contrast, the design of pulse sequences and demonstrates knowledge of the techniques used to solve problems and shows ability to apply these successfully. The minimum percentage required is: 65%

6 (Distinction)

Demonstrated evidence of advanced achievement of course learning outcomes.

Course grade description: Demonstrates an excellent understanding of the theory and practise of Magnetic Resonance Imaging, the source of MR contrast, the design of pulse sequences and demonstrates a proficient knowledge of the techniques used to solve practical problems successfully. The minimum percentage required is: 75%

7 (High Distinction)

Demonstrated evidence of exceptional achievement of course learning outcomes.

Course grade description: Demonstrates an excellent understanding of the theory and practise of Magnetic Resonance Imaging, the source of MR contrast, the design of pulse sequences and demonstrates a highly proficient knowledge of the techniques used to solve both theoretical and practical problems successfully. The minimum percentage required is: 85%

Additional course grading information

To pass this course, students must score at least 45%, which is 23 out of 50, on the final examination to achieve an overall passing grade of 4 or higher.

Supplementary assessment

Supplementary assessment is available for this course.

Should you fail a course with a grade of 3, you may be eligible for supplementary assessment. Refer to my.UQ for information on supplementary assessment and how to apply. 

Supplementary assessment provides an additional opportunity to demonstrate you have achieved all the required learning outcomes for a course.  

If you apply and are granted supplementary assessment, the type of supplementary assessment set will consider which learning outcome(s) have not been met.  

Supplementary assessment in this course will be a 2-hour examination similar in style to the end-of-semester examination. To receive a passing grade of 3S4, you must obtain a mark of 50% or more on the supplementary assessment. 

Additional assessment information

Artificial Intelligence

To pass this course, students will be required to demonstrate a detailed understanding of course material together with a range of associated skills independent of Artificial Intelligence (AI) and Machine Translation (MT) tools.

For assessment tasks that are completed in-person (including examinations) termed “secure assessment”, the use of generative Artificial Intelligence (AI) or Machine Translation (MT) tools will not be permitted unless otherwise advised. Any attempted use of AI or MT may constitute student misconduct under the Student Code of Conduct.

 Other non-secure assessment tasks (such as assignments) are designed to help you develop your understanding and skills, and to prepare you for secure assessment. You are thus generally encouraged to complete such assessment without the use of AI/MT, unless explicitly advised to the contrary in the assessment item. In any event, if you choose to use such tools, then you must clearly reference any such use within your submitted work. A failure to reference AI or MT use may constitute student misconduct under the Student Code of Conduct. 

Applications for Extensions to Assessment Due Dates

Extension requests are submitted online via my.UQ – applying for an extension. Extension requests received in any other way will not be approved. Additional details associated with extension requests, including acceptable and unacceptable reasons, may be found at my.UQ.

Please note:

  • Requests for an extension to an assessment due date must be submitted through your my.UQ portal and you must provide documentation of your circumstances, as soon as it becomes evident that an extension is needed. Your application must be submitted on or before the assessment item's due date and time.
  • Applications for extension can take time to be processed so you should continue to work on your assessment item while awaiting a decision. We recommend that you submit any completed work by the due date, and this will be marked if your application is not approved. Should your application be approved, then you will be able to resubmit by the agreed revised due date.
  • If an extension is approved, you will be notified via your my.UQ portal and the new date and time for submission provided. It is important that you check the revised date as it may differ from the date that you requested.
  • If the basis of the application is a medical condition, applications should be accompanied by a medical certificate dated prior to the assignment due date. If you are unable to provide documentation to support your application by the due date and time you must still submit your application on time and attach a written statement (Word document) outlining why you cannot provide the documentation. You must then upload the documentation to the portal within 24 hours.
  • If an extension is being sought on the basis of exceptional circumstances, it must be accompanied by supporting documentation (eg. Statutory declaration).
  • For extensions based on a SAP you may be granted a maximum of 7 days (if no earlier maximum date applies). See the Extension or Deferral availability section of each assessment for details. Your SAP is all that is required as documentation to support your application. However, additional extension requests for the assessment item will require the submission of additional supporting documentation e.g., a medical certificate. All extension requests must be received by the assessment due date and time.
  • Students may be asked to submit evidence of work completed to date. Lack of adequate progress on your assessment item may result in an extension being denied.
  • If you have been ill or unable to attend class for more than 14 days, you are advised to carefully consider whether you are capable of successfully completing your courses this semester. You might be eligible to withdraw without academic penalty - seek advice from the Faculty that administers your program.
  • There are no provisions for exemption from an assessment item within UQ rules. If you are unable to submit an assessment piece then, under special circumstances, you may be granted an exemption, but may be required to submit alternative assessment to ensure all learning outcomes are met.

 Applications to defer an exam

In certain circumstances you can apply to take a deferred examination for in-semester and end-of-semester exams. You'll need to demonstrate through supporting documentation how unavoidable circumstances prevented you from sitting your exam. If you can’t, you can apply for a one-off discretionary deferred exam.

Deferred Exam requests are submitted online via mySi-net. Requests received in any other way will not be approved. Additional details associated with deferred examinations, including acceptable and unacceptable reasons may be found at my.UQ.

Please note:

  • Applications can be submitted no later than 5 calendar days after the date of the original exam.
  • There are no provisions to defer a deferred exam. You need to be available to sit your deferred examination.
  • Your deferred examination request(s) must have a status of "submitted" in mySI-net to be assessed.
  • All applications for deferred in-semester examinations are assessed by the relevant school. Applications for deferred end-of-semester examinations are assessed by the Academic Services Division.
  • You’ll receive an email to your student email account when the status of your application is updated.
  • If you have a medical condition, mental health condition or disability and require alternative arrangements for your deferred exam you’ll need to complete the online alternative exam arrangements through my.UQ. This is in addition to your deferred examinations request. You need to submit this request on the same day as your request for a deferred exam or supplementary assessment. Contact Student Services if you need assistance completing your alternative exam arrangements request.

Learning resources

You'll need the following resources to successfully complete the course. We've indicated below if you need a personal copy of the reading materials or your own item.

Library resources

Find the required and recommended resources for this course on the UQ Library website.

Additional learning resources information

Students are encouraged to use the UQ Library services.

There is information about facilities available to remote students, including borrowing and photocopy requests. Students are also encouraged to access a number of international databases available through the library. The name and email address of the library contact person are distributed each semester, and students are assured of the librarian's willingness to answer any queries. The UQ Blackboard website is essential to the course. It offers a study schedule, all course resources, lecture recordings, quizzes, access to assessments, and a discussion board. It also provides relevant references and addresses. Students are required to check the Blackboard website regularly.

Learning activities

The learning activities for this course are outlined below. Learn more about the learning outcomes that apply to this course.

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Learning period Activity type Topic
Week 1

(28 Jul - 03 Aug)

Lecture

Module 1 - Introduction: Pulse Sequence Revision.

Module 1 reviews the fundamental concepts of MRI techniques as introduced in MRES7100. Students are required to study the materials on the Blackboard website to familiarise themselves with these concepts.

Week 2

(04 Aug - 10 Aug)

Lecture

Module 2 - RF Pulses: Function, Design, Calibration.

Module 2 covers the functions of radiofrequency (RF) pulses in MRI sequences. The practical aspects, such as Specific Absorption Rate (SAR) and flip angle calibration, of RF pulses will also be covered.

Week 3

(11 Aug - 17 Aug)

Lecture

Module 3 - Pulsed Gradients: Balancing the Equation.

Module 3 explains the magnetic field gradients and theirs role in slice selection, and phase and frequency encoding. It will also explore the spatial encoding of MRI signals.

Week 4

(18 Aug - 24 Aug)

Lecture

Module 4 - Sequence Construction: Contrast Formation and Spatial Encoding.

Module 4 will cover the construction of a conventional gradient-echo and a spin-echo sequence.

Tutorial

Tutorial 1 - Sequence Construction Demonstration.

In this tutorial, we will demonstrate the basic process of constructing a sequence.

Week 5

(25 Aug - 31 Aug)

Lecture

Module 5 - Parallel Imaging

Module 4 covers two parallel imaging techniques: SENSE and GRAPPA. It will also explore their impacts on acquisition time and signal-to-noise ratio (SNR).

Tutorial

Tutorial 2 - Quiz 2 Review.

In this tutorial, we will review the questions from Quiz 2.

Multiple weeks

From Week 6 To Week 8
(01 Sep - 21 Sep)

Case-based learning

Practical Demonstration: DIXON imaging

This one-hour demonstration will showcase the Dixon sequence for fat imaging on a 3T scanner at the Centre for Advanced Imaging (CAI), UQ. The time for the demonstration session will depend on the availability of the scanner and the radiographer, and this will be communicated to the students during the semester. Students are encouraged to observe the demonstration in person at CAI. Recordings of the demonstration will be uploaded to the Blackboard website. Questions for the mid-semester assignment will be based on this demonstration.

Week 6

(01 Sep - 07 Sep)

Lecture

Module 6 - 3D Imaging. Multi-echoes: Dixon, MEDIC.

This module will cover the difference between 2-D and 3-D imaging sequences, the chemical shift of fat, Dixon's method and multi-echo gradient echo acquisition.

Week 7

(08 Sep - 14 Sep)

Lecture

Module 7 - GRE: Steady State - Hahn, DESS, FISP

This module will address the establishment of steady state in imaging. It will discuss three gradient echo sequences: Spoiled, Balanced, and Refocused. The module will also explore the formation of both Hahn echo and Stimulated echo.

Tutorial

Tutorial 3 - Quiz 3 Review

We will review the questions from Quiz 3 in the tutorial.

Week 8

(15 Sep - 21 Sep)

Lecture

Module 8 - GRE: CISS, Feel the VIBE

The module examines two 3D fast steady-state gradient echo sequences: VIBE ad CISS.

Week 9

(22 Sep - 28 Sep)

Lecture

Module 9 - Turbocharged: MPRAGE or MP2RAGE?

This module will discuss three frequently-used imaging sequences: TurboFLASH, MPRAGE and MP2RAGE.

Tutorial

Tutorial 4 - Quiz 4 Review.

We will review the questions from Quiz 4 in the tutorial.

Mid Sem break

(29 Sep - 05 Oct)

No student involvement (Breaks, information)

In-Semester break

Mid-semester break

Week 10

(06 Oct - 12 Oct)

No student involvement (Breaks, information)

QLD public holiday - King's Birthday.

Week 11

(13 Oct - 19 Oct)

Lecture

Module 10 - FLAIR, DIR. Making HASTE.

This module will cover fast spin-echo sequences, including fast spin echo (FSE), HASTE, SPACE and FLAIR. Dual inversion recovery method will also be introduced.

Week 12

(20 Oct - 26 Oct)

Lecture

Module 11 - Spotting trouble: Static and Motion Artefacts.

This module examines some of the most common static artefacts on MRI images, discussing their origin, manifestation, and potential remedy methods.

Tutorial

Tutorial 5 - Quiz 5 Review.

We will review the questions from Quiz 5 in the tutorial.

Week 13

(27 Oct - 02 Nov)

Tutorial

Course Revision

Revision and catch-ups.

Additional learning activity information

Tutorials are not held every week. All lectures and tutorials will be recorded and uploaded shortly after the corresponding sessions. 

Policies and procedures

University policies and procedures apply to all aspects of student life. As a UQ student, you must comply with University-wide and program-specific requirements, including the:

Learn more about UQ policies on my.UQ and the Policy and Procedure Library.