Course coordinator
Dr Danial Saifuddin
Course overview
- Study period
- Semester 2, 2024 (22/07/2024 - 18/11/2024)
- Study level
- Postgraduate Coursework
- Location
- Dutton Park
- Attendance mode
- In Person
- Units
- 4
- Administrative campus
- Dutton Park
- Coordinating unit
- Pharmacy School
Students taking this course will have the opportunity to engage in experimental and theoretical skill development in pharmaceutical analysis and quality assurance in pharmaceutics. They will also be exposed to the intricacies of pre-clinical research, how research uses animal models and the ethical boundaries. The course will provide highlight the role of pharmacodynamics, pharmacokinetics and toxicology as well as emphasise the need for collection of safety data in the early stages of drug development. Students will learn about the type of and need for recording results and the documentation. The students will meet a career professional and learn about the practical application of the knowledge gained within the course. The theoretical aspects of the course are supported by a large pharmaceutical analysis and pharmaceutical quality assurance individual research project that involves analysis of drug concentrations using industry standard techniques with an emphasis on analytical design, method development and interpretation of findings both in report form and oral defence.
Welcome to the course profile for PHIP7122, a part of the Masters of Pharmaceutical Industry Practice. Please email or see the course co-ordinator for any questions you have regarding the course information.
Course requirements
Restrictions
MPharmIndPrac students only
Course contact
Course staff
Lecturer
Dr Danial Saifuddin
Professor Irina Vetter
Dr Md Moniruzzaman
Dr Farzaneh Forouz
Guest lecturer
Dr Fekade Sime
Tutor
Mr Yifan Wang
Mr Junkai Zhang
Ms Min-Tz Weng
Dr Fekade Sime
Timetable
The timetable for this course is available on the UQ Public Timetable.
Additional timetable information
All timetable information will be detailed in the blackboard site for this course.
Aims and outcomes
This course aims to develop your knowledge and capacity in perspectivesﾠof the general theme ofﾠpreclinical drug discovery, with a specific focus on: preclinical drug and device discovery, animal ethics, pharmacokinetics, pharmacodynamics, toxicology, qualitiy assurance in pharmaceuticals, drug analysis, research learning, and communicating science.
ﾠ
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Learning outcomes
After successfully completing this course you should be able to:
LO1.
Contextualise the role Preclinical Drug Discovery has in the drug life cycle
LO2.
Identify and explain the role of toxicology in light of preclinical and clinical drug evaluation
LO3.
Apply the principles of pharmacodynamics and pharmacokinetics
LO4.
Justify the role of animal research and the ensuing ethical considerations and regulatory processes
LO5.
Collaborate and apply skills in research learning
LO6.
Design and deliver a presentation on scientific research
Assessment
Assessment summary
| Category | Assessment task | Weight | Due date |
|---|---|---|---|
| Presentation, Poster |
Poster Presentation of Preclinical Research
|
20% |
19/08/2024 - 26/08/2024
The poster will be submitted prior to the poster presentation session, and the same poster will be presented at the assigned time. Workshop sessions will be used for presentation times. Please refer to the schedule in the Blackboard site timetable. |
| Paper/ Report/ Annotation |
Pharmaceutical Analysis Research Project Report
|
20% |
2/09/2024 3:00 pm |
| Quiz |
Pharmacokinetic and Pharmacodynamic Online Quiz
|
10% |
13/09/2024 3:00 pm
The quiz will be be opened 7 days before the due date. |
| Quiz |
Toxicology Quiz
|
10% |
16/09/2024 3:00 pm
The quiz will be be opened 7 days before the due date. |
| Paper/ Report/ Annotation, Project |
Quality Assurance Research Project
|
40% |
4/11/2024 3:00 pm |
Assessment details
Poster Presentation of Preclinical Research
- Identity Verified
- In-person
- Online
- Mode
- Oral, Product/ Artefact/ Multimedia
- Category
- Presentation, Poster
- Weight
- 20%
- Due date
19/08/2024 - 26/08/2024
The poster will be submitted prior to the poster presentation session, and the same poster will be presented at the assigned time. Workshop sessions will be used for presentation times. Please refer to the schedule in the Blackboard site timetable.
- Learning outcomes
- L01, L02, L04, L06
Task description
The poster presentation will focus on preclinical drug discovery topics, including in vitro and in vivo research methods for various diseases, on a topic that will be assigned to each student.
- A single PowerPoint slide as an electronic poster will be submitted prior to the assigned poster presentation session.
- The poster will be presented within the poster presentation session during a scheduled workshop.
- Further details for slide preparation and presentation schedule will be provided on Blackboard.
- This task is assessed by two rubrics: one for the oral presentation and one for the poster. 50% of marks are allocated to each assessment.
The presentation will be recorded and retained as per university policy. The recording will be stored in a secure manner and will only be accessed if required for the purposes of moderation of marking; provision of feedback to the student; and/or re-marking following a successful re-mark application.
This task has been designed to be challenging, authentic and complex. Whilst students may use Artificial Intelligence (AI) technologies, successful completion of assessment in this course will require students to critically engage in specific contexts and tasks for which artificial intelligence will provide only limited support and guidance. To pass this assessment, students will be required to demonstrate detailed comprehension independent of AI tools.
Submission guidelines
The poster file is to be submitted via Blackboard before the presentation, and the presentation will be in class as scheduled on the Blackboard site.
Deferral or extension
You may be able to apply for an extension.
The maximum extension allowed is 28 days. Extensions are given in multiples of 24 hours.
Late submission
A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.
Pharmaceutical Analysis Research Project Report
- Mode
- Written
- Category
- Paper/ Report/ Annotation
- Weight
- 20%
- Due date
2/09/2024 3:00 pm
- Other conditions
- Student specific.
- Learning outcomes
- L05
Task description
The pharmaceutical analysis research project report requires students to analyse a data pack in the form of an excel document (unique to each individual student, assigned by student number). The data pack includes data from a simulated experiment analysing the active ingredient in a set of tablets in which the students will use a graphing program, GraphPad Prism, to determine the contents of the active ingredient within the data set and comment on whether it passes the test. The related tutorial session will cover the methods of analysis. The tasks for the report will be found on blackboard.
This task has been designed to be challenging, authentic and complex. Whilst students may use Artificial Intelligence (AI) and Machine Translation (MT) technologies, successful completion of the assessment will require students to critically engage in specific contexts and tasks for which AI will provide only limited support and guidance. A failure to reference AI or MT use may constitute student misconduct under the Student Code of Conduct. To pass this assessment, students will be required to demonstrate detailed comprehension of their written submission independent of AI and MT tools.
Submission guidelines
Submission via Turnitin link provided in the Blackboard site.
Deferral or extension
You may be able to apply for an extension.
The maximum extension allowed is 28 days. Extensions are given in multiples of 24 hours.
Late submission
A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.
Pharmacokinetic and Pharmacodynamic Online Quiz
- Online
- Mode
- Written
- Category
- Quiz
- Weight
- 10%
- Due date
13/09/2024 3:00 pm
The quiz will be be opened 7 days before the due date.
- Other conditions
- Time limited.
- Learning outcomes
- L03
Task description
The quiz will assess the content from the Pharmacokinetics and Pharmacodynamics module within the course.
- One attempt is permitted for this quiz.
- The quiz duration is 30 minutes. An additional 15 minutes is provided as a buffer for any issues that might arise during your quiz.
- The format may be a mixture of question types, for example: multiple choice, multiple answer, matching, ordering, fill in the blank/s, jumbled sentence/s, either/or (e.g. true/false), short answer, and short essay style questions.
- Questions may be provided randomly from a pool, therefore each student may receive a different but equivalent quiz.
- The quiz will be marked electronically, correct answers will be awarded the marks indicated beside the question, and incorrect answers will be awarded zero.
- This is an individual assessment that you are required to undertake without any form of communication with other students.
Submission guidelines
Complete the quiz online via the Link provided at Learn.UQ (Blackboard) any time in the 7 days prior to the submission deadline.
Deferral or extension
You may be able to apply for an extension.
The maximum extension allowed is 28 days. Extensions are given in multiples of 24 hours.
Late submission
A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.
Toxicology Quiz
- Online
- Mode
- Written
- Category
- Quiz
- Weight
- 10%
- Due date
16/09/2024 3:00 pm
The quiz will be be opened 7 days before the due date.
- Other conditions
- Time limited.
- Learning outcomes
- L02
Task description
The quiz will assess the content from the toxicology module within the course.
- One attempt is permitted for this quiz.
- The quiz duration is 30 minutes. An additional 15 minutes is provided as a buffer for any issues that might arise during your quiz.
- The format may be a mixture of question types, for example: multiple choice, multiple answer, matching, ordering, fill in the blank/s, jumbled sentence/s, either/or (e.g. true/false), short answer, and short essay style questions.
- Questions may be provided randomly from a pool, therefore each student may receive a different but equivalent quiz.
- The quiz will be marked electronically, correct answers will be awarded the marks indicated beside the question, and incorrect answers will be awarded zero.
- This is an individual assessment that you are required to undertake without any form of communication with other students.
Submission guidelines
Complete the quiz online via the Link provided at Learn.UQ (Blackboard) any time in the 7 days prior to the submission deadline.
Deferral or extension
You may be able to apply for an extension.
The maximum extension allowed is 28 days. Extensions are given in multiples of 24 hours.
Late submission
A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.
Quality Assurance Research Project
- Team or group-based
- Mode
- Written
- Category
- Paper/ Report/ Annotation, Project
- Weight
- 40%
- Due date
4/11/2024 3:00 pm
- Other conditions
- Peer assessment factor.
- Learning outcomes
- L05
Task description
The detailed task requirements can be found on the Blackboard site. The Quality Assurance research project will be based on what was conducted during the practical sessions, where British Pharmacopeia assessments will be performed on pharmaceutical tablets. The results from the practical will be presented within the report and assessed against the rubrics provided on the Blackboard site. Reports are required to address the tasks described in the practical guide and the rubric attached to the Blackboard site. One report is to be submitted by each team, and team members are responsible for ensuring submission is completed.
The assessment is divided into three parts: the project report (30% of semester marks submitted as a group), the laboratory records submitted as an individual and assessed as an individual (5% of the semester), and the peer contribution assessment (5% of the semester).
This task has been designed to be challenging, authentic and complex. Whilst students may use Artificial Intelligence (AI) and Machine Translation (MT) technologies, successful completion of the assessment will require students to critically engage in specific contexts and tasks for which AI will provide only limited support and guidance. A failure to reference AI or MT use may constitute student misconduct under the Student Code of Conduct. To pass this assessment, students will be required to demonstrate detailed comprehension of their written submission independent of AI and MT tools.
Submission guidelines
Submission via Blackboard for peer mark and report. Laboratory books submission via office.
Deferral or extension
You may be able to apply for an extension.
The maximum extension allowed is 28 days. Extensions are given in multiples of 24 hours.
Late submission
A penalty of 10% of the maximum possible mark will be deducted per 24 hours from time submission is due for up to 7 days. After 7 days, you will receive a mark of 0.
Course grading
Full criteria for each grade is available in the Assessment Procedure.
| Grade | Cut off Percent | Description |
|---|---|---|
| 1 (Low Fail) | 1 - 29 |
Absence of evidence of achievement of course learning outcomes. |
| 2 (Fail) | 30 - 44 |
Minimal evidence of achievement of course learning outcomes. |
| 3 (Marginal Fail) | 45 - 49 |
Demonstrated evidence of developing achievement of course learning outcomes |
| 4 (Pass) | 50 - 64 |
Demonstrated evidence of functional achievement of course learning outcomes. |
| 5 (Credit) | 65 - 74 |
Demonstrated evidence of proficient achievement of course learning outcomes. |
| 6 (Distinction) | 75 - 84 |
Demonstrated evidence of advanced achievement of course learning outcomes. |
| 7 (High Distinction) | 85 - 100 |
Demonstrated evidence of exceptional achievement of course learning outcomes. |
Supplementary assessment
Supplementary assessment is available for this course.
Learning resources
You'll need the following resources to successfully complete the course. We've indicated below if you need a personal copy of the reading materials or your own item.
Library resources
Find the required and recommended resources for this course on the UQ Library website.
Other course materials
If we've listed something under further requirement, you'll need to provide your own.
Required
| Item | Description | Further Requirement |
|---|---|---|
| Laboratory coat | For your health and safety, you will not be allowed to enter the laboratory without this item. Laboratory coats can be acquired from the School Locker on the St Lucia campus or relevant scientific health and safety stores. | own item needed |
| Laboratory safety glasses | For your health and safety, you will not be allowed to enter the laboratory without this item. Laboratory safety glasses can be acquired from the School Locker on the St Lucia campus or relevant scientific health and safety stores. | own item needed |
Additional learning resources information
Zoom: Access to Zoom via your UQ student account will be required for certain synchronous online classes each week (workshops).
Learning activities
The learning activities for this course are outlined below. Learn more about the learning outcomes that apply to this course.
Filter activity type by
Please select
| Learning period | Activity type | Topic |
|---|---|---|
Multiple weeks From Week 1 To Week 2 |
Workshop |
Preclinical Drug Discovery and Animal Ethics Learning outcomes: L01, L04, L06 |
Multiple weeks From Week 3 To Week 7 |
Workshop |
Pharmacokinetics Learning outcomes: L01, L05 |
Multiple weeks From Week 6 To Week 8 |
Workshop |
Toxicology Learning outcomes: L02 |
Multiple weeks From Week 6 To Week 13 |
Practical |
Pharmaceutical Analysis and Quality Assurance Practicals are held on Wednesday in Week 6 and Weeks 10-13. These sessions will be laboratory based and requires personal protective equipment such as laboratory coat and laboratory safety glasses. The practicals will involve quality assurance assays on pharmaceutical tablets. The practicals are split into two sessions: morning (9am to 12pm) and afternoon (2pm to 5pm). Students will work in groups and submit a group assignment report outlined in the assessment section (Quality Assurance Research Project). Specific dates, time and location are detailed on Blackboard. Learning outcomes: L01, L05 |
Multiple weeks From Week 9 To Week 11 |
Workshop |
Industry Expert Engagement Workshops with Industry experts relevant to the course, presented by the guest lecturer. Learning outcomes: L01, L02, L03 |
Policies and procedures
University policies and procedures apply to all aspects of student life. As a UQ student, you must comply with University-wide and program-specific requirements, including the:
- Student Code of Conduct Policy
- Student Integrity and Misconduct Policy and Procedure
- Assessment Procedure
- Examinations Procedure
- Reasonable Adjustments - Students Policy and Procedure
Learn more about UQ policies on my.UQ and the Policy and Procedure Library.
You'll also need to be aware of the following policies and procedures while completing this course:
- Laboratory Occupational Health and Safety