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Course profile

Principles of Disease II (VETS2007)

Study period
Sem 2 2024
Location
Gatton
Attendance mode
In Person

Course overview

Study period
Semester 2, 2024 (22/07/2024 - 18/11/2024)
Study level
Undergraduate
Location
Gatton
Attendance mode
In Person
Units
2
Administrative campus
Gatton
Coordinating unit
Veterinary Science School

A gross, microscopic & molecular perspective on how hosts respond to disease agents, & the outcomes of the disease process; general pathology & immunology.

The purpose of this course is to prepare students for the study of specific diseases by explaining how the host responds to disease agents, and the outcomes of the disease process in terms of gross, microscopic and molecular alterations in cells and tissues (i.e. general pathology and immunology).ᅠ An introduction to the general principles of pharmacology and toxicology is also included in the course.

Course requirements

Assumed background

Students in this course are assumed to have a sound knowledge of:

  • invertebrate animal zoology and basic cell biology (VETS1060, AGRC1021, AGRC1041, ANIM1020 or equivalent courses)ᅠᅠ
  • cellular biochemistry, molecular assemblies and metabolic processes (from BIOC1011)
  • gross and microscopic anatomy of domestic animals (from VETS1003ᅠand VETS2011)
  • the factors that influence disease occurrence and impact (from VETS1018 and VETS2006)
  • the basic structure and life cycle of the major groups of parasites, fungi, bacteria and viruses that infect animals (from VETS2006)
  • the components of the immune system, their functions and interactions (from VETS2006)

Prerequisites

You'll need to complete the following courses before enrolling in this one:

AGRC1041 or ANIM1020, VETS2006

Incompatible

You can't enrol in this course if you've already completed the following:

ANIM2504

Restrictions

Enrolment is restricted to BVSc(Hons) and BVetTech students only.

Course contact

Course staff

Timetable

The timetable for this course is available on the UQ Public Timetable.

Additional timetable information

Please be aware that due to unforeseen circumstances it may be necessary to make changes to the timetable throughout the semester and so it is important to check VETS2007 Blackboard site regularly. Students will be notified of changes to the timetable via Blackboard Announcements.

Aims and outcomes

The aim of this course is to prepare students for the study of specific diseases by explaining how the host responds to disease agents, and the outcomes of the disease process in terms of gross, microscopic and molecular alterations in cells and tissues (i.e. general pathology and immunology).

Learning outcomes

After successfully completing this course you should be able to:

LO1.

Recognise and differentiate pathological processes at the gross and microscopic levels

LO2.

Differentiate and explain the pathogenesis and general effects of degenerative processes, disturbances of normal blood circulation, inflammation, tissue repair, growth disturbances and neoplastic diseases.

LO3.

Explain the role of immune mechanisms in the production of pathological changes and disease and in the response to different pathogens and to tumours. Demonstrate your understanding of the mechanisms underlying neonatal immunology.

LO4.

Explain the principles of vaccination and serological tests and the rational use or interpretation of these in the control and diagnosis of animal diseases.

LO5.

Describe how drugs enter the body and distribute to target sites. Explain the potential benefits and dangers of drug administration to animals.

LO6.

Demonstrate your understanding of the fundamental principles of toxicology, including the spectrum of toxin sources for animals and describe the factors influencing toxicity of substances.

LO7.

Apply general pathology knowledge to describe the clinical and pathological manifestation of disease in case-based scenarios and formulate the most appropriate differential diagnosis

LO8.

Work together in small groups to critically analyze a case-based scenario on general pathology.

Assessment

Assessment summary

Category Assessment task Weight Due date
Examination In semester examination
  • Identity Verified
  • In-person
35%

In-semester Saturday

31/08/2024 - 14/09/2024

Essay/ Critique, Quiz, Tutorial/ Problem Set Pathology case study
  • Team or group-based
15%

14/10/2024 12:00 pm

Examination End of semester examination
  • Identity Verified
  • In-person
50%

End of Semester Exam Period

2/11/2024 - 16/11/2024

Assessment details

In semester examination

  • Identity Verified
  • In-person
Mode
Written
Category
Examination
Weight
35%
Due date

In-semester Saturday

31/08/2024 - 14/09/2024

Learning outcomes
L01, L02

Task description

This will be a central on-campus examination hosted on Inspera held on Saturday the 14th of September 2024. This exam covers circulatory disorders (3 lectures), necrosis, apoptosis, molecular basis of cell damage and aging, intracellular and extracellular accumulation, pathological calcifications (5 lectures), inflammation and tissue repair (3 lectures), growth/developmental disorders and neoplasia (3 lectures), histopathology practicals (4 practicals). The exam will incorporate a range of questions available in the Inspera examination platform.  

 

 

Exam details

Planning time 10 minutes
Duration 60 minutes
Calculator options

No calculators permitted

Open/closed book Closed Book examination - no written materials permitted
Exam platform Inspera
Invigilation

Invigilated in person

Submission guidelines

Deferral or extension

You may be able to defer this exam.

Pathology case study

  • Team or group-based
Mode
Written
Category
Essay/ Critique, Quiz, Tutorial/ Problem Set
Weight
15%
Due date

14/10/2024 12:00 pm

Learning outcomes
L02, L04, L07, L08

Task description

General pathology short answer and/or multiple choice questions assignment, consisting of one case scenario with integrative questions. Questions are uploaded on the blackboard at the end of week 9.

Submission guidelines

Students are encouraged to work in small groups and submit a single assignment as an electronic copy (on a word document) via the online submission portal (in the assessment section of the blackboard) by 09 am on the 14th of October. Before submitting your work, you are encouraged to read the UQ academic integrity and plagiarism policy (PPL 3.60.04) and understand its implication.

Deferral or extension

You may be able to apply for an extension.

The maximum extension allowed is 7 days. Extensions are given in multiples of 24 hours.

Late submission

Failure to submit the pathology case studies by the due date will incur an academic penalty of 10% per 24 hours of the maximum possible mark for the assessment item in the first 7 periods of 24 hours.

End of semester examination

  • Identity Verified
  • In-person
Mode
Written
Category
Examination
Weight
50%
Due date

End of Semester Exam Period

2/11/2024 - 16/11/2024

Learning outcomes
L01, L03, L04, L05, L06

Task description

This will be an on-campus invigilated examination hosted on Inspera. The exam will assess material not covered in the In Semester examination (toxicology, pharmacology, serological tests, methodologies in disease investigation, applied immunology and immunopathology). The exam will incorporate a range of questions available in the Inspera examination platform. 

Exam details

Planning time 10 minutes
Duration 90 minutes
Calculator options

No calculators permitted

Open/closed book Closed Book examination - no written materials permitted
Exam platform Inspera
Invigilation

Invigilated in person

Submission guidelines

Deferral or extension

You may be able to defer this exam.

Course grading

Full criteria for each grade is available in the Assessment Procedure.

Grade Description
1 (Low Fail)

Absence of evidence of achievement of course learning outcomes.

Course grade description: 0-29%

2 (Fail)

Minimal evidence of achievement of course learning outcomes.

Course grade description: 30-44%

3 (Marginal Fail)

Demonstrated evidence of developing achievement of course learning outcomes

Course grade description: 45-49%

4 (Pass)

Demonstrated evidence of functional achievement of course learning outcomes.

Course grade description: 50-64%

5 (Credit)

Demonstrated evidence of proficient achievement of course learning outcomes.

Course grade description: 65-74%

6 (Distinction)

Demonstrated evidence of advanced achievement of course learning outcomes.

Course grade description: 75-84%

7 (High Distinction)

Demonstrated evidence of exceptional achievement of course learning outcomes.

Course grade description: 85-100%

Additional course grading information

To pass the course, a student must achieve at least 50% for the course overall.ᅠ

Supplementary assessment

Supplementary assessment is available for this course.

Should you fail a course with a grade of 3, you may be eligible for supplementary assessment. Refer to my.UQ for information on supplementary assessment and how to apply. 

Supplementary assessment provides an additional opportunity to demonstrate you have achieved all the required learning outcomes for a course.  

If you apply and are granted supplementary assessment, the type of supplementary assessment set will consider which learning outcome(s) have not been met.  

Supplementary assessment can take any form (such as a written report, oral presentation, examination or other appropriate assessment) and may test specific learning outcomes tailored to the individual student, or all learning outcomes. 

To receive a passing grade of 3S4, you must obtain a mark of 50% or more on the supplementary assessment. 

Additional assessment information

For INSPERA exams, the summary page shows a ‘SUBMIT NOW’ button that students must click to submit their answers. After submission, students will receive a confirmation on the dashboard that they have submitted and can no longer edit responses. For all End of Semester exams with durations of 60, 90, 120 or 180 minutes you will receive an additional 10 minutes of planning time to read the examination questions and plan your responses, but you may commence working if you wish. It’s essential that you check before the exam that your laptop meets the device requirements for Inspera assessments. If you do not own a suitable laptop, you can borrow one from the LibraryGet familiar with Inspera provides the most up to date information for students about using Inspera. Power outlets will not be available during exams

Learning resources

You'll need the following resources to successfully complete the course. We've indicated below if you need a personal copy of the reading materials or your own item.

Library resources

Find the required and recommended resources for this course on the UQ Library website.

Additional learning resources information

Ensuring work-life balance and seeking help at an early stage are key attributes for successful study at university. UQ Student Servicesᅠand the Student Union (UQU) provide many resources for students studying at UQ. Student Services provide a range of mindfulness programs and counselling services to help improve confidence and overall wellbeing. UQU also provide a range of student support, welfare and wellbeing resources.

If immediate help is needed, please call the 24/7ᅠUQ Counselling and Crisis Line 1300 851 998 


The histopathology glass slides have been Aperio-scanned and can be viewed using the ImageScope program. Instructions for ImageScope will be available on Blackboard. It will also be possible to upload the slide files to your laptop (Further instructions will be available on Blackboard and discussed during the histopath prac class). In addition, the scanned slides can be accessible through the BEST Slice platform.

If you can't access eLearn then it is most likely that you are using an outdated web browser. Blackboard recommends that you use: Internet Explorer 8 or late, Firefox 3.6 or later, Chrome. For more information about browser compatibility, see here: Browser not compatible with Learn.UQ - eLearning - University of Queensland.

 Other learning resources that may help with the interpretation of the gross and histological pictures:

  1) Noah's arkive from the CL Davis and Samuel Wesley Thompson DVM Foundation website (the largest collection of gross and histological images of different pathological lesions in a broad range of species) Noah’s Arkive – The Davis-Thompson Foundation (davisthompsonfoundation.org)

  2) Veterinary Systemic Pathology Online - VSPO (collection of histological cases, including scanned slides, of different conditions grouped by system, species or aetiology)

  https://www.askjpc.org/vspo/index.php

Learning activities

The learning activities for this course are outlined below. Learn more about the learning outcomes that apply to this course.

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Learning period Activity type Topic
Multiple weeks

From Week 1 To Week 5
(22 Jul - 25 Aug)

Practical

Pathology prac classes

A practical class in gross pathology (examination of abattoir specimens) and 4 practical classes in histopathology

Learning outcomes: L01, L02

Multiple weeks

From Week 1 To Week 4
(22 Jul - 18 Aug)

Lecture

Pathology

A series of 5 lectures on mechanisms of cell injury and cell death, necrosis, apoptosis, intracellular accumulations and pathological calcifications, cell ageing, 3 lectures on inflammation and repair, 3 lectures on circulatory disorders, 3 lectures on growth and developmental disorders and neoplasia. A prerecorded introduction to basic pathology and histopathology will be available on BB.

Learning outcomes: L02

Multiple weeks

From Week 5 To Week 6
(19 Aug - 01 Sep)

Lecture

Pharmacology

A series of 6 lectures on pharmacology.

Learning outcomes: L05

Week 6

(26 Aug - 01 Sep)

Lecture

Toxicology

An introduction to the concepts of drugs and natural chemicals that cause harm to animals (2 lectures).

Learning outcomes: L06

Multiple weeks

From Week 8 To Week 13
(09 Sep - 27 Oct)

Tutorial

Q&A sessions

Two Q&A session with practice questions in preparation to the mid-semester examination and the end of semester examination.

Learning outcomes: L01, L02, L03, L04, L05, L06, L07

Week 8

(09 Sep - 15 Sep)

Tutorial

Gross pathology tutorial

A tutorial on gross lesions of the different pathological processes learnt during the course.

Learning outcomes: L01

Multiple weeks

From Week 9 To Week 13
(16 Sep - 27 Oct)

Case-based learning

Case-based scenarios on general pathology

A tutorial on case-based scenarios on circulatory disorders, inflammation, neoplasia, immunopathology.

Learning outcomes: L03, L07, L08

Lecture

Applied Immunology and Immunopathology

A series of 10 lectures on applied immunology, covering the following topics: tumour immunity, vaccine, serological tests, mucosal immunity and mechanisms of microbial infection, immune response to viruses/bacteria/parasites/fungi, neonatal immunity, immunodeficiency, hypersensitivity reactions, autoimmune diseases.

Learning outcomes: L03, L04

Week 9

(16 Sep - 22 Sep)

Lecture

Methodologies in disease investigation

One lecture on diagnostic techniques to investigate diseases at various levels in animals.

Learning outcomes: L04, L07

Week 10

(30 Sep - 06 Oct)

Tutorial

Serology tutorial

Serology tutorial (2 hours; all students).

Learning outcomes: L04

Week 13

(21 Oct - 27 Oct)

Tutorial

Pharmacology Tutorials

Pharmacology tutorials (2 hours; all students).

Learning outcomes: L05

Additional learning activity information

Lectures

The lectures provide basic information on all components of the course (pathology, immunology, immunopathology, toxicology and pharmacology). Lecture notes or summaries, sample exam questions, and/or powerpoint notes will be made available prior to the start of each lecture.

 

Practical classes and tutorials

The practical classes and tutorials reinforce lecture material and in general use a problem-based approach, utilising clinical cases. The lecturers may direct students to additional readings should certain topics require further information or clarification. Students will be expected to have read the relevant course notes before practical sessions and tutorials (case-based scenarios).         

Policies and procedures

University policies and procedures apply to all aspects of student life. As a UQ student, you must comply with University-wide and program-specific requirements, including the:

Learn more about UQ policies on my.UQ and the Policy and Procedure Library.

You'll also need to be aware of the following policies and procedures while completing this course: